5% DEXTROSE Infusion
Dextrose 5%
Claris Lifesciences Ltd
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Indications
5% DEXTROSE Infusion is used for:
Parenteral Nutrition and Hydration, Hypoglycemia, Hyperkalaemia
Adult Dose
As water replacement: Replacement should be to recover losses and maintenance therapy.
Child Dose
As water replacement: Replacement should be to recover losses and maintenance therapy.
Renal Dose
Administration
Contra Indications
Known allergy to corn or corn products. Diabetic coma with hyperglycaemia. Use of hypertonic solutions in patients with intracranial or intraspinal haemorrhage. Patients with delirium tremens and dehydration. Anuria, hepatic coma, or glucose-galactose malabsorption syndrome.
Precautions
Overt or known subclinical DM. Patients with carbohydrate intolerance. IV admin of dextrose may result in hypokalaemia, hypophosphataemia and hypomagnesemia. Prolonged infusion of isotonic dextrose solutions may cause water intoxication. Production of insulin may be adversely affected by prolonged parenteral nutrition with dextrose solutions. Rapid admin of hypertonic dextrose solutions may result in hyperglycaemia and hyperosmolar syndrome. Monitor for signs of mental confusion or loss of consciousness.
Monitor blood and urinary glucose regularly. Caution when used in very low birth weight infants. Abrupt withdrawal may lead to rebound hypoglycaemia. Caution when used parenterally in pregnant women.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Dextrose 5% :
Venous thrombosis, phlebitis, hypovolemia, hypervolemia, dehydration, oedema, fever, mental confusion, unconsciousness, hyperosmolar syndrome, hyperglycaemia, hypokalaemia, acidosis, hypophosphataemia, hypomagnesemia, polyuria, glycosuria, ketonuria, nausea, diarrhoea, polydipsia, vein irritation, tissue necrosis, pulmonary oedema, tachypnoea.
Mechanism of Action
Dextrose is a monosaccharide that is used as a source of calories and water for hydration. It helps to reduce loss of body protein and nitrogen. It also promotes glycogen deposition in the liver. When used with insulin, it stimulates the uptake of potassium by cells, especially in muscle tissue, thus lowering serum potassium levels.
Note
5% DEXTROSE Infusion manufactured by Claris Lifesciences Ltd. Its generic name is Dextrose 5%. 5% DEXTROSE is availble in Nepal.
Farmaco Nepal drug index information on 5% DEXTROSE Infusion is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.