Acal 250 Tablet
Calcium Carbonate
250mg
Acme Laboratories Ltd
| Pack size | 1 |
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Available as:
Indications
Acal 250 Tablet is used for:
Heartburn, Indigestion, Calcium deficiency, Hypocalcaemia, Hyperphosphatemia, Calcium supplement, Stomach upset
Adult Dose
Adult: PO Hyperacidity: Take 1-2 tab as needed, up to a max of 16 tab/day. May suck or chew tablets.
Hyperphosphataemia in chronic renal failure Initial: 2.5 g/day, up to 17 g/day in divided doses.
Child Dose
Renal Dose
Renal impairment:
CrCl (ml/min)
<25 Dosage adjustments may be needed depending on serum calcium levels.
Administration
May be taken with or without food. Take w/ meals for better absorption. Avoid taking w/ large amount of fibre-rich food.
Contra Indications
Patients with Ca renal calculi or history of renal calculi; hypercalcaemia; hypophosphataemia. Patients with suspected digoxin toxicity.
Precautions
Renal impairment, hypoparathyroid disease, hypercalcaemia-associated diseases. Calcium absorption is impaired in achlorhydria; use an alternate salt and take with food. Caution when used in patients with a history of kidney stones.
Lactation: Safe; crosses the placenta; appears in breast milk
Pregnancy-Lactation
Interactions
Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication.
Adverse Effects
Side effects of Calcium Carbonate :
Anorexia, nausea, vomiting, constipation, flatulence; hypercalcaemia; metabolic alkalosis; milk-alkali syndrome, tissue-calcification. Gastric hypersecretion and acid rebound (with prolonged use).
Mechanism of Action
Calcium carbonate can neutralise gastric acid rapidly and effectively. However, it may adversely activate Ca dependent processes, leading to secretion of gastric and hydrochloric acid. It can induce rebound acid secretion and, prolonged high doses may cause hypercalcemia, alkalosis and milk-alkali syndrome.
Note
Acal 250 250mg Tablet manufactured by Acme Laboratories Ltd. Its generic name is Calcium Carbonate. Acal 250 is availble in Nepal.
Farmaco Nepal drug index information on Acal 250 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.