Acivir Eye Ointment
Acyclovir 3% Eye prep
3% w/v
Cipla Ltd.
| Pack size | 5gm |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 74.52 NPR |
Indications
Acivir Eye Ointment is used for:
Herpes simplex keratitis
Adult Dose
As 3% oint: Apply 5 times/day until 3rd day of complete healing.
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration.
Pregnancy-Lactation
Interactions
Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects w/ drugs that affect renal physiology (e.g. ciclosporin, tacrolimus).
Adverse Effects
Side effects of Acyclovir 3% Eye prep :
Eye application may produce stinging, superficial punctate keratopathy, blepharitis or conjunctivitis.
Mechanism of Action
Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.
Note
Acivir 3% w/v Eye Ointment manufactured by Cipla Ltd.. Its generic name is Acyclovir 3% Eye prep. Acivir is availble in Nepal.
Farmaco Nepal drug index information on Acivir Eye Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.