Act Hib Capsule
Influenza vaccine inactivated (split virion)
Sanofi India Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price |
Available as:
Indications
Act Hib Capsule is used for:
Prevention of influenza caused by Influenza Virus types A and B in adults and children aged 6 months and over.
Adult Dose
Parenteral
Active immunisation against influenza
Adult: 0.5 ml as a single dose via IM/SC inj.
Child Dose
Parenteral
Active immunisation against influenza
Child: 6-3 yr: 0.25-0.5 ml; 3-12 yr: 0.5 ml. Repeat dose at least 4 wk later if child was not previously vaccinated.
Doses may be given via IM/SC admin.
Renal Dose
Administration
IM or deep SC injection.
Contra Indications
Known anaphylactic hypersensitivity reactions to egg proteins (eggs or egg products), chicken proteins, or any other component of the vaccine including traces (formaldehyde, octoxino
l 9 (Triton X-100) and neomycin).
Immunisation should not be performed during a febrile or acute illness.
Precautions
Since this vaccine contains traces of formaldehyde, octoxinol 9 (Triton X-100) and neomycin due to the use of these substances during production, it should be used with caution in subjects with a hypersensitivity to any of these substances.
Patients with a history of Guillain-Barré Syndrome (GBS) with an onset related in time to influenza vaccination may be at increased risk of again developing GBS if given influenza vaccine.
Use in pregnancy & lactation: Safety of use during pregnancy has not been established; benefits of vaccination should be weighed against potential risks. However, as an inactivated vaccine, it does not share the theoretical risks associated with live vaccines.
It is not known if this is excreted in human milk; hence, caution should used when administering vaccine to breastfeed ing women. However, as an inactivated vaccine, it does not share the theoretical risks associated with live vaccines.
Pregnancy-Lactation
Use in pregnancy: Safety of use during pregnancy has not been established; benefits of vaccination should be weighed against potential risks. However, as an inactivated vaccine, it does not share the theoretical risks associated with live vaccines.
Interactions
Immunosuppressants, antineoplastics or high doses of corticosteroids may reduce response to vaccines. Increased antibody response with aldesleukin and aspirin. May possibly increase anticoagulant effects of warfarin.
Adverse Effects
Side effects of Influenza vaccine inactivated (split virion) :
In children under 5 years of age, systemic reactions (e.g. fever, malaise, myalgia) may be more pronounced.
Local Reactions: Erythema (redness), swelling, pain, ecchymosis, induration.
Systemic Reactions: Fever, malaise, shivering, fatigue, headache, sweating, joint and muscular pain. These reactions usually disappear within 1-2 days without treatment.
Rarely: Neuralgia, paresthesia, convulsions and transient thrombocytopenia Allergic reactions leading to shock in rare cases. Vasculitis with transient renal involvement, in very rare cases.
Mechanism of Action
Influenza virus vaccine inactivated promotes immunity to influenza virus by inducing specific antibody formation.
Note
Act Hib Capsule manufactured by Sanofi India Ltd.. Its generic name is Influenza vaccine inactivated (split virion). Act Hib is availble in Nepal.
Farmaco Nepal drug index information on Act Hib Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.