Active P Tablet
Acetaminophen (paracetamol) + Triprolidine HCl + Phenylephrine HCl
Alive Pharmaceutical. Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.00 NPR |
Indications
Active P Tablet is used for:
Fever with common cold, nasal congestion and allergic rhinitis
Adult Dose
Oral
Adult
Tablet
1 tablet 6 hourly
Child Dose
Oral
Child > 12 years: 1 tablet 6 hourly
Child 6-11 years: 1/2 tablet 6 hourly
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity
Precautions
Renal and hepatic impairment. Pregnancy and lactation. Severe constipation,intestinal obstruction, anuria.
Glaucoma, asthma or COPD, hypertension, heart disease, coronary artery disease, or a thyroid disorder.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Acetaminophen (paracetamol) + Triprolidine HCl + Phenylephrine HCl :
Serious side effect such as:
fast or uneven heart rate; mood changes; tremor, seizure (convulsions); easy bruising or bleeding, unusual weakness; urinating less than usual or not at all; feeling short of breath; or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).
Less serious side effects may include:
dizziness, drowsiness; dry mouth, nose, or throat; constipation; blurred vision; or feeling nervous or restless.
Mechanism of Action
Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS.
Triprolidine blocks the action of endogenous histamine by binding to H1 receptor. It is useful for the prevention and suppression of the signs and symptoms of allergic rhinitis and other upper resp allergies.
Phenylephrine is a sympathomimetic with mainly direct effects on alpha-adrenergic receptors and weak beta-adrenergic activity. It causes vasoconstriction of the arterioles of the nasal mucosa and conjunctiva; activates the dilator muscle of the pupil to cause contraction; produces vasoconstriction of arterioles in the body and produces systemic arterial vasoconstriction.
Note
Active P Tablet manufactured by Alive Pharmaceutical. Pvt. Ltd.. Its generic name is Acetaminophen (paracetamol) + Triprolidine HCl + Phenylephrine HCl. Active P is availble in Nepal.
Farmaco Nepal drug index information on Active P Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.