Acular Eye Drop
Ketorolac Tromethamine 0.5% Eye prep
0.5%
Allergan India Pvt. Ltd.
| Pack size | |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 67.87 NPR |
Available as:
Indications
Acular Eye Drop is used for:
Allergic conjunctivitis, Postoperative eye inflammation, Cystoid macular oedema
Adult Dose
Allergic Conjunctivitis
Indicated for temporary relief of ocular itching caused by seasonal allergic conjunctivitis
Instill 1 drop in affected eye(s) q6hr
Ocular Pain & Inflammation
Indicated for pain and inflammation following catarac surgery
Instill 1 drop in affected eye(s) four times daily starting 24 hr after surgery and continue up to 4 days after surgery
Ocular Pain & Burning/Stinging
Indicated to reduce ocular pain and burning/stinging following corneal refractive surgery
Instill 1 drop in the operated eye PRN for up to 4 days postoperatively
Child Dose
<2 years: Safety and efficacy not established
Allergic Conjunctivitis
Indicated for temporary relief of ocular itching caused by seasonal allergic conjunctivitis
>2 years: Instill 1 drop in affected eye(s) q6hr (Acular)
Ocular Pain & Inflammation
>2 years: Instill 1 drop (Acular) in affected eye(s) q6hr starting 24 hr after surgery and continue through the first 2 weeks postoperatively
Ocular Pain & Burning/Stinging
Indicated to reduce ocular pain and burning/stinging following corneal refractive surgery
>2 years: Instill 1 drop (Acular LS) in operated eye PRN for up to 4 days postoperatively
Renal Dose
Administration
Contra Indications
Ketorolac Tromethamine is contraindicated in patients with known hypersensitivity to NSAIDs and any of the components of Ketorolac Tromethamine. Moreover, the patient with the history of asthma, nasal polyp, angioedema, peptic ulcer and bleeding, bleeding disorders are contraindicated for this drug.
Precautions
Elderly, hepatic dysfunction, heart failure, predisposition to reduced blood volume or renal blood flow. Mild renal impairment; monitor renal function closely.
Lactation: Unknown; use with caution
Pregnancy-Lactation
Interactions
May reduce effects of antihypertensives eg ACE inhibitors or angiotensin II receptor antagonists (AIIA). Increased risk of renal toxicity with ACE inhibitors, diuretics. Increased adverse effects with aspirin or other NSAIDs. Hallucinations may occur when used with fluoxetine, thiothixene, alprazolam.
Potentially Fatal: Increased risk of GI bleeding with warfarin. May increase toxicity of methotrexate (MTX) and lithium. Increased plasma concentrations with probenecid.
Adverse Effects
Side effects of Ketorolac Tromethamine 0.5% Eye prep :
>10%
Transient ocular burning/stinging
1-10%
Conjunctival hyperemia,Corneal edema,Iritis,Corneal infiltrates,Iritis,Corneal edema,Ocular inflammation,Ocular irritation,Ocular pain,Increased ocular pressure,Superficial keratitis,Superficial ocular infection
<1%
Blurred vision,Corneal ulcer,Corneal erosion,Corneal thinning,Perforation of cornea,Dry eyes,Epithelial breakdown,Corneal epithelial degeneration
Mechanism of Action
Ketorolac inhibits prostaglandin synthesis by decreasing the activity of the cyclooxygenase enzyme.
Note
Acular 0.5% Eye Drop manufactured by Allergan India Pvt. Ltd.. Its generic name is Ketorolac Tromethamine 0.5% Eye prep. Acular is availble in Nepal.
Farmaco Nepal drug index information on Acular Eye Drop is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.