Afee Capsule
Ferrous Sulphate + Folic Acid + Vitamin C
Apex Pharmaceuticals Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.00 NPR |
Available as:
Indications
Afee Capsule is used for:
Iron, Folic acid, Vitamin-C deficiency, Pregnancy and lactation
Adult Dose
Adults: 1-2 tablets or 1-2 tsf syrup daily or as directed by the physician.
Child Dose
Renal Dose
Administration
For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation
Contra Indications
Contraindicated in patients with a known hypersensitivity to any of the ingredients of this product.
Precautions
Caution should be taken in the conditions where there is a risk of iron overload, such as haemochromatosis, thalassemia, haemosiderosis or haemolytic anaemia.
Lactation: Present in breast milk, use caution
Pregnancy-Lactation
Interactions
Elemental iron: Antacids may decrease the absorption of carbonyl iron.
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.
Adverse Effects
Side effects of Ferrous Sulphate + Folic Acid + Vitamin C :
A few side-effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur.
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Vitamin C is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.
Note
Afee Capsule manufactured by Apex Pharmaceuticals Pvt. Ltd.. Its generic name is Ferrous Sulphate + Folic Acid + Vitamin C. Afee is availble in Nepal.
Farmaco Nepal drug index information on Afee Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.