Airtec SF 250 Inhaler
Salmeterol + Fluticasone
25mcg + 250mcg
Glenmark Pharmaceuticals Ltd.
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| Retail Price | 676.79 NPR |
Indications
Airtec SF 250 Inhaler is used for:
Chronic Asthma, COPD
Adult Dose
Inhalation
Asthma
Adult: As combination containing salmeterol 50 mcg and fluticasone propionate 100/250/500 mcg/dose of inhalation powder:
1 inhalation bid.
As combination containing salmeterol 25 mcg and fluticasone propionate 50/125/250 mcg/dose of pressurised inhalation:
2 inhalation bid.
Chronic obstructive pulmonary disease
Adult: As combination containing salmeterol 50 mcg and fluticasone propionate 500 mcg/dose of inhalation powder:
1 inhalation bid.
Child Dose
Inhalation
Asthma
Child: 4-12 yr:
As combination containing salmeterol 50 mcg and fluticasone propionate 100 mcg/ dose of inhalation powder:
1 inhalation bid;
As combination containing salmeterol 25 mcg and fluticasone propionate 50 mcg/dose of pressurised inhalation:
2 inhalation bid.
>12 yr: As combination containing salmeterol 50 mcg and fluticasone propionate 100/250/500 mcg/dose of inhalation powder:
1 inhalation bid;
As combination containing salmeterol 50/125/250 mcg and fluticasone propionate 50 mcg/dose of pressurised inhalation:
2 inhalation bid.
Renal Dose
Administration
Contra Indications
Not for primary treatment of status asthmaticus or other acute attacks of asthma. Severe hypersensitivity to milk proteins.
Precautions
Pulmonary TB, severe cardiovascular disorders, heart rhythm abnormalities, DM, thyrotoxicosis, hypokalaemia. Patients at risk of decreased bone mineral content (e.g. smoking, old age, sedentary lifestyle, poor nutrition, family history of osteoporosis or long term use of drugs that may decrease bone mass (e.g. anticonvulsants and corticosteroids). Do not stop therapy abruptly; therapy should be down titrated. Advise patient to rinse mouth after inhalation. Monitor height of children on prolonged therapy. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Increased fluticasone levels with CYP 3A4 inhibitors e.g ritonavir, ketoconazole, itraconazole. Additive effects with other beta-agonist.
Adverse Effects
Side effects of Salmeterol + Fluticasone :
>10%
Upper respiratory tract infection (21-27%),Headache (12-21%),Pharyngitis (10-13%)
1-10%
Candidiasis, nonspecific site (0-10%),Throat irritation (7-9%), Musculoskeletal pain (2-9%), Bronchitis (2-8%),Upper respiratory inflammation (4-7%),Viral respiratory infections (4-6%),Nausea or vomiting (4-6%),Cough (3-6%),Sinusitis (4-5%),Hoarseness or dysphonia (2-5%),Fever (3-4%),Diarrhea (2-4%),Gastrointestinal (GI) discomfort or pain (1-4%),Oral candidiasis (1-4%),Muscle cramps or spasms (3%),Malaise or fatigue (2-3%),Viral GI infections (0-3%)
Potentially Fatal: Paradoxical bronchospasm.
Mechanism of Action
Salmeterol, a long acting beta 2-agonist which acts locally in the lung to mediate bronchodilation. Fluticasone, a corticosteroid with mainly glucocorticoid activity, reduce symptoms and exacerbations of asthma.
Note
Airtec SF 250 25mcg + 250mcg Inhaler manufactured by Glenmark Pharmaceuticals Ltd.. Its generic name is Salmeterol + Fluticasone. Airtec SF 250 is availble in Nepal.
Farmaco Nepal drug index information on Airtec SF 250 Inhaler is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.