Albutamol S Tablet
Salbutamol + Etofylline + Bromhexine
2mg + 8mg + 200mg
Centaur Pharmaceuticals Pvt. Ltd.
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| Retail Price | 2.45 NPR |
Indications
Albutamol S Tablet is used for:
Bronchial asthma, chronic asthmatic bronchitis, emphysema, COPD & as an adjunct to antibacterials in respiratory infections associated with bronchospasm.
Adult Dose
Oral
Adult
1-2 tabs tid-qid
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity
Precautions
Hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation, HTN, DM, glaucoma, hypokalaemia, seizure disorder. Renal impairment. Elderly. Pregnancy and lactation. Monitoring Parameters Monitor BP, heart rate, electrolyte and fluid balance; glucose, lactate and K levels.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Salbutamol + Etofylline + Bromhexine :
Tremor, nervousness, nausea and vomiting, tachycardia, palpitations, chest pain, shakiness, dizziness, headache, insomnia, inhalation site sensation, hyperactivity, HTN, hypotension, increased sweating, allergic reactions, DM, muscle cramps, flu-like syndrome, conjunctivitis, UTI, hypokalaemia,. Rarely, erythema multiforme, Stevens-Johnson syndrome.
Potentially Fatal: Paradoxical bronchospasm.
Mechanism of Action
Salbutamol activates adenyl cyclase, the enzyme that stimulates the production of cyclic adenosine-3', 5'-monophosphate (cAMP). Increased cAMP leads to activation of protein kinase A, which inhibits phosphorylation of myosin and lowers intracellular ionic Ca concentrations, resulting in smooth muscle relaxation.
Bromhexine enhances mucus transport by reducing mucus viscosity and by activating the ciliated epithelium (mucociliary clearance). This secretolytic and secretomotor effect in the bronchial tract area relieves cough and facilitates expectoration.
Note
Albutamol S 2mg + 8mg + 200mg Tablet manufactured by Centaur Pharmaceuticals Pvt. Ltd.. Its generic name is Salbutamol + Etofylline + Bromhexine. Albutamol S is availble in Nepal.
Farmaco Nepal drug index information on Albutamol S Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.