Allerfen 120 Tablet
Fexofenadine Hydrochloride
120mg
Sumy Pharmaceuticals Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 9.00 NPR |
Available as:
Indications
Allerfen 120 Tablet is used for:
Allergic rhinitis, Hay fever, Urticaria, Allergy
Adult Dose
Adults:
Allergic rhinitis: 120 mg once daily or 60 mg twice daily
Urticaria: 180 mg once daily
Child Dose
Children:
Tablet
2-12 years: 30 mg (1 spoonful) or 5 ml twice daily
6 months-2 years: 15 mg (1/2 spoonful) or 2.5 ml twice daily
>12 years: 60 mg PO BID OR 180 mg PO qDay
ODT
6-12 years: 30 mg PO BID
Renal Dose
Adult: Initially, 60 mg once daily.
Child: 6 mth-<2 yr: 15 mg once daily and 2-11 yr: 30 mg once daily.
>12 years: 60 mg PO qDay, initially
Administration
Should be taken on an empty stomach. Take before meals. Do not take w/ fruit juice.
Contra Indications
Hypersensitivity.
Precautions
Renal impairment. Pregnancy, lactation; children <6 yr.
Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Pregnancy-Lactation
Interactions
Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin.
Adverse Effects
Side effects of Fexofenadine Hydrochloride :
>10%
Vomiting (6-12%)
1-10%
Headache (5-10%),Cough (4%),Diarrhea (3-4%),URTI (3%),Back pain (2-3%),Pyrexia (2%),Dysmenorrhea (2%),Dizziness (2%),Stomach discomfort (2%),Pain in extremity (2%),Somnolence (1-3%),Rhinorrhea (1-2%)
Mechanism of Action
Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract.
Note
Allerfen 120 120mg Tablet manufactured by Sumy Pharmaceuticals Pvt. Ltd.. Its generic name is Fexofenadine Hydrochloride. Allerfen 120 is availble in Nepal.
Farmaco Nepal drug index information on Allerfen 120 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.