Amicor Injection
Amrinone (Inamrinone)
5mg
Samarth Life Sciences Pvt Ltd
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| Retail Price | 911.81 NPR |
Indications
Amicor Injection is used for:
Congestive Heart failure
Adult Dose
Intravenous
Heart failure
Adult: Loading dose: 750 mcg/kg by slow inj over 2-3 min (may be repeated after 30 minutes if necessary). Maintenance: 5-10 mcg/kg/min by infusion. Max cumulative dose: 10 mg/kg in 24 hr.
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Obstructive pulmonary or aortic disease, hypertrophic cardiomyopathy; BP and heart rate monitored during drug administration; fluid and electrolyte balance should be maintained; platelet counts and liver function should be monitored; protect amp from light. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Chemical interaction with precipitation occurs with amrinone and dextrose or furosemide. Thus drug mixing should be avoided.
Potentially Fatal: Concurrent usage with disopyramide may lead to severe hypotension.
Adverse Effects
Side effects of Amrinone (Inamrinone) :
GI disturbances, nausea, vomiting, thrombocytopaenia, hypotension, chest pain, hypersensitivity, myositis, vasculitis, nail discoloration, Inj site pain, decreased tear production.
Potentially Fatal: Cardiac arrhythmia, hepatotoxicity.
Mechanism of Action
Amrinone is a phosphodiesterase inhibitor which has vasodilating and positive inotropic properties. It causes an increase in cyclic adenosine monophosphate conc leading to greater contractile force in cardiac muscle.
Note
Amicor 5mg Injection manufactured by Samarth Life Sciences Pvt Ltd. Its generic name is Amrinone (Inamrinone). Amicor is availble in Nepal.
Farmaco Nepal drug index information on Amicor Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.