Anomycetin Ointment
Chloramphenicol 1% Eye prep
Akums Drugs And Pharmaceuticals Ltd.
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Indications
Anomycetin Ointment is used for:
Bacterial Conjunctivitis
Adult Dose
Ocular infections Adult: Apply a 1% ointment 3-4 times daily.
Hepatic impairment: Dose reduction may be required.
Child Dose
Renal Dose
Renal impairment: Dose reduction may be required.
Administration
Contra Indications
History of hypersensitivity to the drug; Herpes simplex and other virul conditions of the eye, mycosis.
Precautions
Avoid prolonged use. Discontinue immediately if local hypersensitivity reactions occur.
Pregnancy-Lactation
Interactions
Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives.
Potentially Fatal: Increases the effect of oral anticoagulants, oral hypoglycaemic agents, phenytoin. Avoid concomitant administration with drugs that depress bone marrow function.
Adverse Effects
Side effects of Chloramphenicol 1% Eye prep :
Ophthalmic application: Hypersensitivity reactions including rashes, fever and angioedema.
Mechanism of Action
Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.
Note
Anomycetin Ointment manufactured by Akums Drugs And Pharmaceuticals Ltd.. Its generic name is Chloramphenicol 1% Eye prep. Anomycetin is availble in Nepal.
Farmaco Nepal drug index information on Anomycetin Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.