Apnicaf Injection
Caffeine
20mg
Abbott India Ltd.
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Available as:
Indications
Apnicaf Injection is used for:
Migraine, Mild stimulant of the central nervous system, Short-term treatment of neonatal apnoea of prematurity
Adult Dose
Oral
Migraine
Adult: 100 mg in combination with ergotamine.
Mild stimulant of the central nervous system
Adult: 50-100 mg up to 200 mg. Not to be taken more often than 3 hrly. Max: 1 g/day.
Max Dosage: 1 g daily.
Child Dose
Intravenous
Short-term treatment of neonatal apnoea of prematurity
Child: As citrate: 20 mg/kg (equivalent to 10 mg/kg caffeine) via IV infusion.
Maintenance: 5 mg/kg daily. May also be given orally.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity.
Precautions
Peptic ulceration; symptomatic cardiac arrhythmias and/or palpitations; 1st several days to wk after an acute MI; neonates; pregnancy; lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Caffeine :
Insomnia, restlessness, nervousness, mild delirium; nausea, vomiting, gastric irritation.
Mechanism of Action
Caffeine, a methylxanthine, is a phosphodiesterase inhibitor. It has an antagonistic effect at central adenosine receptors. It is a CNS and resp stimulant. It has bronchodilating and diuretic properties and it facilitates the performance of muscular work.
Note
Apnicaf 20mg Injection manufactured by Abbott India Ltd.. Its generic name is Caffeine. Apnicaf is availble in Nepal.
Farmaco Nepal drug index information on Apnicaf Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.