Arcetrin Syrup

Cetirizine
Arya Pharma Lab Pvt. Ltd.
Pack size 30ml/60ml
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Indications

Arcetrin Syrup is used for: Allergic rhinitis, Hay fever, Allergies, Urticaria

Adult Dose

Oral Allergic conditions Adult: 10 mg once daily or 5 mg bid. Elderly: Initially, 5 mg once daily. Hepatic impairment: Initially, 5 mg once daily. Syrup: Adults: 2 teaspoon once daily or 1 teaspoon twice daily.

Child Dose

Oral Allergic conditions Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses. Syrup: Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily. Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily. <2 years: Safety and efficacy not established

Renal Dose

Renal impairment GFR >50 mL/min: Dose adjustment not necessary GFR ? 50 mL/min: 5 mg PO qDay Peritoneal dialysis: 5 mg PO qDay Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity; lactation.

Precautions

Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy. Lactation: Excreted in breast milk; use not recommended

Pregnancy-Lactation

Interactions

Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).

Adverse Effects

Side effects of Cetirizine : >10% Somnolence (2-14%),Headache (11-14%) 1-10% Fatigue (5.9%),Dry mouth (5%),Dizziness (2%),Diarrhea (2-3%),Malaise (4%),Bronchospasm (2-3%),Vomiting (2-3%),Epistaxis (2-4%) <1% Stomach pain,Drowsiness,Angioedema,Fussiness,Hallucinations,Hypotension,Tremor,Tongue discoloration

Mechanism of Action

Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.

Note

Arcetrin Syrup manufactured by Arya Pharma Lab Pvt. Ltd.. Its generic name is Cetirizine. Arcetrin is availble in Nepal. Farmaco Nepal drug index information on Arcetrin Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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