Astine Tablet
Ebastine
10mg
Nepal Pharmaceuticals Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 8.00 NPR |
Available as:
Indications
Astine Tablet is used for:
Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria
Adult Dose
Oral
Allergic conditions
Adult: 10-20 mg once daily.
Child Dose
Oral
Allergic conditions
Child: >6 yr: 5 mg once daily.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity, cardiac arrhythmias.
Precautions
Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.
Adverse Effects
Side effects of Ebastine :
Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia.
Mechanism of Action
Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions.
Note
Astine 10mg Tablet manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Ebastine. Astine is availble in Nepal.
Farmaco Nepal drug index information on Astine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.