Astine Tablet

Ebastine
10mg
Nepal Pharmaceuticals Pvt. Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 8.00 NPR

Available as:

Indications

Astine Tablet is used for: Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria

Adult Dose

Oral Allergic conditions Adult: 10-20 mg once daily.

Child Dose

Oral Allergic conditions Child: >6 yr: 5 mg once daily.

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity, cardiac arrhythmias.

Precautions

Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation.

Pregnancy-Lactation

Interactions

Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.

Adverse Effects

Side effects of Ebastine : Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia.

Mechanism of Action

Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions.

Note

Astine 10mg Tablet manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Ebastine. Astine is availble in Nepal. Farmaco Nepal drug index information on Astine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Ebastine :