Aziderm Cream
Azelaic Acid topical
Micro Labs Ltd.
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Indications
Aziderm Cream is used for:
Acne vulgaris, Rosacea, Rosacea melasma, Post inflammatory hyperpigmentation
Adult Dose
Topical
Acne vulgaris
Adult: Apply into the affected areas bid (morning and evening). Improvement may be detectable w/n 4 wk. Duration of treatment: Up to 6 mth.
Topical
Rosacea
Adult: Apply into the affected areas bid (morning and evening). Improvement occurs in 4-8 wk.
Child Dose
Topical
Acne vulgaris, Rosacea
Child: >12 yr Same as adult dose.
<12 years: Safety and efficacy not established
Renal Dose
Administration
Cleanse affected area with mild soap or soapless cleansing lotion and pat dry before applying. Apply thinly into the affected areas bid (morning and evening) after cleansing.
Contra Indications
Hypersensitivity to any of the ingredients.
Precautions
Pregnancy, lactation. Avoid contact with eyes, mouth or other mucous membranes. Occlusive dressings or wrappings should not be used. Recommend patient to use only very mild soaps or soapless cleansing lotions for facial washing. Monitor for hypopigmentation in patients with dark complexion. Safety and efficacy not established in children <12 yr.
Lactation: enters breast milk; use with caution
Pregnancy-Lactation
Interactions
There have been no formal studies of the interaction of Azelaic Acid Gel with other drugs.
Adverse Effects
Side effects of Azelaic Acid topical :
>10%
Burning/ stinging/ tingling (4-16%)
1-10%
Pruritus (1-6%),Scaling/ dry skin/ xerosis (1-5%),Erythema/ irritation (1-2%)
<1%
Contact dermatitis,Edema,Acne
Mechanism of Action
Azelaic acid is a naturally-occurring aliphatic dicarboxylic acid. The exact mechanism of action in treatment of acne vulgaries has not been fully established. It is believed to inhibit the growth of susceptible organisms (mainly Propionibacteria Acnes) on the skin surface, and inhibits follicular keratinisation thus restricts the development of comedones. Mechanism of action in the treatment of rosacea is unknown.
Note
Aziderm Cream manufactured by Micro Labs Ltd.. Its generic name is Azelaic Acid topical. Aziderm is availble in Nepal.
Farmaco Nepal drug index information on Aziderm Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.