Beclasone GM Ointment
Beclomethasone + Gentamicin + Miconazole Topical
Emcure Pharmaceuticals Ltd.
| Pack size | 5g |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 13.90 NPR |
Indications
Beclasone GM Ointment is used for:
Dermatoses where secondary bacterial and/or candidal infection present.
Impetigo, Furunculosis, Secondary infected dermatoses, Napkin rashes, Otitis externa, Intertringinous eruptions, Atopic and discoid eczema, dermatitis, psoriasis, lichen simplex, discoid lupus erythematosus.
Adult Dose
Topical
As Cream/Ointment
Sufficient quantity should be applied bid-tid to cover completely affected skin area.
Child Dose
Safety & Efficacy not established.
Renal Dose
Administration
Contra Indications
Hypersensitivity to any of the ingredients.
Rosacea, acne, peri-oral dermatitis, tuberculosis of the skin and varicose ulcers. Skin lesions caused by infections with viruses (e.g. herpes simplex, vaccinia or varicella), fungi (e.g. candida, tinea) or bacteria (e.g. impetigo).
Precautions
For external use only. Do not use in or around the eye.
Not recommended during prenancy & breast feeding.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Beclomethasone + Gentamicin + Miconazole Topical :
Prolonged and intensive treatment may cause local atrophic changes in the skin such as stria, thinning, loss of elasticity, dilatation of the superficial blood vessels, telangiectasia and ecchymosis.
Prolonged use, use of large amounts, treatment of extensive areas, or application to damaged skin, when is used and when the occlusive dressing technique is applied can result in sufficient systemic absorption to produce the features of hypercortisonism such as depression of the hypothalamic-pituitaryadrenal axis with consequent suppression of the adrenal gland. These effects are most likely to be severe in infants and children. Growth may be retarded and a Cushingoid state may be produced.
Benign intracranial hypertension has been reported less frequently. In infants the napkin may act as an occlusive dressing, and hence these preparations should not be used in the
nappy area for flexural eruptions. Ideally they should not be used in infants and young children at all.
Mechanism of Action
Beclomethasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes and fibroblasts, and reverses capillary permeability and lysosomal stabilization at the cellular level to prevent or control inflammation.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Gentamicin binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.
Note
Beclasone GM Ointment manufactured by Emcure Pharmaceuticals Ltd.. Its generic name is Beclomethasone + Gentamicin + Miconazole Topical. Beclasone GM is availble in Nepal.
Farmaco Nepal drug index information on Beclasone GM Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.