Betavate C Cream
Betamethasone + Clioquinol Topical
0.1%W/V + 3%W/W
National Healthcare Pvt. Ltd.
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| Retail Price | 55.00 NPR |
Indications
Betavate C Cream is used for:
Eczema, prurigo nodularis, psoriasis, lichen simplex chronicus, lichen planus, seborrhoeic dermatitis, Otitis externa
Adult Dose
Topical
Apply 2-3 times a day in to the affected area for 2-4 weeks.
Child Dose
Topical
Child > 2 years: Apply 2-3 times a day in to the affected area for 2-4 weeks.
Renal Dose
Administration
This medicine is for external use on the affected areas of skin only. The cream or ointment should be applied thinly to the affected areas of skin. Wash hands thoroughly after applying this medicine, unless the hands are the area being treated.
Contra Indications
Hypersensitivity, Child under 2 years of age, widespread plaque psoriasis, acne, itching around the anus or genitals, fungal infections, such as ringworm, athletes foot or thrush, viral infections, such as cold sores, herpes or chicken pox
Precautions
Prolonged use with occlusive dressings may cause the body to produce lower levels of the hormone cortisol than normal. Caution applying this to the face over a long period of time as it may cause skin thinning, to the eyelids to make sure it does not get into eye as there may be a risk of developing glaucoma or cataracts.
Using this for a prolonged period of time there is a possibility of develop a cataract.
Cautious using large quantities for a prolonged period or treating a large area of the body. This medicine may be absorbed through the skin and into blood stream which can result in the following symptoms of hypercortisolism developing; stretch marks, the appearance of blood vessels under the surface of skin, increased body hair growth, changes in skin colour, skin thinning, weight gain or rounding of the face (moon face).
Prolonged use or use under occlusive dressings may result in damage to the nervous system.
Do not use this medicine on a child under 2 years of age.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Betamethasone + Clioquinol Topical :
Common (affects less than 1 in 10 people)
local skin burning or pain
itchy skin
Very rare (affects less than 1 in 10,000 people)
Use this for a long period of time, or use under an airtight dressing, may cause the following symptoms:
stretch marks may develop
the appearance of blood vessels under the surface of your skin
increased body hair growth
changes in skin colour
thinning of your skin and it may also damage more easily
skin wrinkling
skin dryness
weight gain / obesity
rounding of the face (moon face)
hair loss / lack of hair growth / damaged looking hair
These are more likely to happen in infants and children.
Mechanism of Action
Betamethasone is a corticosteroid with mainly glucocorticoid activity. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes, inhibiting macrophage accumulation in inflamed areas, reducing leukocyte adhesion to capillary endothelium, reducing capillary wall permeability and edema formation, decreasing complement components, antagonizing histamine activity and release of kinin from substrates, and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.
Clioquinol is a halogenated hydroxyquinoline with antibacterial and antifungal activity.
Note
Betavate C 0.1%W/V + 3%W/W Cream manufactured by National Healthcare Pvt. Ltd.. Its generic name is Betamethasone + Clioquinol Topical. Betavate C is availble in Nepal.
Farmaco Nepal drug index information on Betavate C Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.