Betnovate N Cream
Betamethasone 0.1% + Neomycin Sulphate 0.5% Topical
0.1 % w/w + 0.5 % w/w
Glaxo SmithKline Pharmaceuticals Ltd.
| Pack size | 20gm |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 44.08 NPR |
Indications
Betnovate N Cream is used for:
Lichen planus, Psoriasis, Eczema, Contact dermatitis, Seborrhoeic dermatitis, Systemic lupus erythematosus, Lichen simplex, Prurigo nodularis
Adult Dose
Adult: Topical Apply 2-3 times/day. Usual duration: Up to 7 days/course.
Child Dose
Child: >2 yr: As cream/ointment: Apply onto the affected area(s) 2-3 times daily. Usual treatment duration: Up to 5 days/course.
Renal Dose
Renal impairment: Dose reduction may be necessary.
Administration
Contra Indications
Hypersensitivity. Rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus and primary cutaneous viral infections. Not to be used in otitis externa complicated by ear-drum perforation. Treatment of primary infected skin lesions caused by fungi or bacteria; primary or secondary infections due to yeast; or secondary infections due to Pseudomonas or Proteus species.
Precautions
Avoid prolonged treatment as it may lead to systemic corticosteroid effects even withour occlusion. Avoid prolonged excessive application to the facial areas. Withdraw treatment if there is spread of the infection. Risk of glaucoma development if preparation enters eye(s). Regular monitoring is recommended when used in psoriasis due to treatment tolerance, rebound relapses, generalised pustular psoriasis or systemic toxicity. Increased risk of contact sensitisation when used for extended period or recurrently. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
If there is significant systemic absorption, neomycin sulfate may increase the respiratory depressant effects of neuromuscular blockers.
Adverse Effects
Side effects of Betamethasone 0.1% + Neomycin Sulphate 0.5% Topical :
Prolonged use may cause local atrophic changes in the skin e.g. thining, striae and dilatation of superficial blood vessels. Local skin burning sensation, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis. Ophthalmic preparation: Corneal ulceration, increased intraocular pressure, mydriasis, ptosis, epithelial punctate keratitis.
Mechanism of Action
Betamethasone valerate is a corticosteroid which is effective in inflammatory dermatoses. It is also effective in less responsive conditions such as psoriasis. Neomycin sulfate is a broad spectrum antibiotic. It is bactericidal against many bacteria which are commonly associated with skin infections.
Note
Betnovate N 0.1 % w/w + 0.5 % w/w Cream manufactured by Glaxo SmithKline Pharmaceuticals Ltd.. Its generic name is Betamethasone 0.1% + Neomycin Sulphate 0.5% Topical. Betnovate N is availble in Nepal.
Farmaco Nepal drug index information on Betnovate N Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.