Buscalm Tablet
Buspirone
5mg
Wockhardt Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 2.22 NPR |
Available as:
Indications
Buscalm Tablet is used for:
Anxiety
Adult Dose
Anxiety Disorders
10-15 mg/day PO divided q8-12hr; may increase every 2-3 days by 5 mg/day to 15-30 mg/day PO divided q8-12hr; not to exceed 60 mg/day
Hepatic impairment: Not recommended for patients with severe impairment
Child Dose
Renal Dose
Renal impairment: Not recommended for patients with severe impairment
Administration
May be taken with or without food. Take consistently either always w/ or always w/o meals.
Contra Indications
Hypersensitivity. Epilepsy; severe renal or hepatic impairment; children <18 yr; pregnancy, lactation.
Precautions
Preceding co-administration of MAOIs, decreased hepatic or renal function. In patients on benzodiazepines, withdraw the drug gradually. May impair ability to drive or operate machinery.
Lactation: Excretion in milk unknown/not recommended
Pregnancy-Lactation
Interactions
Enhanced sedative effects with alcohol or CNS depressants. Increases serum haloperidol. Concurrent admin with MAOIs may lead to increase in BP.
Potentially Fatal: Elevation of BP when taken concomitantly with MAOIs.
Adverse Effects
Side effects of Buspirone :
>10%
Dizziness (12%)
1-10%
Drowsiness (10%),Nausea (8%),Headache (6%),Nervousness (5%),Blurred vision (2%),Confusion (2%),Diarrhea (2%),Excitement (2%),Insomnia (2%),Myalgia (1%),Numbness (2%),Paresthesia (1%),Rash (1%),Tremor (1%),Weakness (2%),Nasal congestion (1%),Sore throat (1%),Nonspecific chest pain (1%),Tinnitus (1%),Dream disturbances (1%)
<1%
Akathisia,Allergic reaction,Anorexia,Bruising,Galactorrhea,Heart failure,Menstrual irregularity,Suicidal ideation,Syncope,Alopecia,Eosinophilia,Edema,Enuresis,Increased ocular pressure,Visual disturbances,Rectal bleeding,Photophobia,Dystonia
Mechanism of Action
Buspirone exerts anxiolytic activity through high affinity for serotonin 5-HT1A and 5-HT2 receptors. It has moderate affinity for dopamine D2-receptors but no affinity for GABA receptors.
Note
Buscalm 5mg Tablet manufactured by Wockhardt Ltd.. Its generic name is Buspirone. Buscalm is availble in Nepal.
Farmaco Nepal drug index information on Buscalm Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.