Bypro Tablet
Bicalutamide
50mg
Fresenius Kabi pharmaceuticals
| Pack size | |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 65.40 NPR |
Indications
Bypro Tablet is used for:
Prostate Cancer
Adult Dose
Oral
Palliative treatment of advanced prostate cancer
Adult: When used with gonadorelin analogue: Usual dose: 50 mg once daily. May be started with or at least 3 days before starting gonadorelin analogue therapy.
Monotherapy or adjuvant therapy to surgery or radiotherapy in locally advanced prostatic cancer
Adult: 150 mg once daily.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity. Females, children. Pregnancy, lactation.
Precautions
Monitor liver function regularly in hepatically impaired patients on prolonged therapy. Monitoring serum levels of Prostate Specific Antigen (PSA) may be useful in evaluating the patient's clincial progress.
Lactation: Bicalutamide is not indicated for use in women.
Pregnancy-Lactation
Interactions
Enhances effect of coumarin anticoagulants.
Adverse Effects
Side effects of Bicalutamide :
>10%
Hot flashes (53%),General pain (35%),Back pain (25%),Asthenia (22%),Constipation (22%),Pelvic pain (21%),Infection (18%),Nausea (15%),Dyspnea (13%),Edema (13%),Peripheral edema (13%),Diarrhea (12%),Hematuria (12%),Nocturia (12%),Abdominal pain (11%),Anemia (11%)
1-10%
Gynecomastia (9%),Rash (9%),UTI (9%),Chest pain (8%),Hypertension (8%),Vomiting (8%),Flu like symptoms (7%),Headache (7%),LFTs elevation (7%),Weight loss (7%),Anorexia (6%),Breast pain (6%),Anxiety (5%)
Arthritis (5%)
Mechanism of Action
Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin, thus preventing the growth of normal and malignant prostatic tissue.
Note
Bypro 50mg Tablet manufactured by Fresenius Kabi pharmaceuticals. Its generic name is Bicalutamide. Bypro is availble in Nepal.
Farmaco Nepal drug index information on Bypro Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.