Bypro Tablet

Bicalutamide
50mg
Fresenius Kabi pharmaceuticals
Pack size
Dispensing mode
Source
Agent
Retail Price 65.40 NPR

Indications

Bypro Tablet is used for: Prostate Cancer

Adult Dose

Oral Palliative treatment of advanced prostate cancer Adult: When used with gonadorelin analogue: Usual dose: 50 mg once daily. May be started with or at least 3 days before starting gonadorelin analogue therapy. Monotherapy or adjuvant therapy to surgery or radiotherapy in locally advanced prostatic cancer Adult: 150 mg once daily.

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity. Females, children. Pregnancy, lactation.

Precautions

Monitor liver function regularly in hepatically impaired patients on prolonged therapy. Monitoring serum levels of Prostate Specific Antigen (PSA) may be useful in evaluating the patient's clincial progress. Lactation: Bicalutamide is not indicated for use in women.

Pregnancy-Lactation

Interactions

Enhances effect of coumarin anticoagulants.

Adverse Effects

Side effects of Bicalutamide : >10% Hot flashes (53%),General pain (35%),Back pain (25%),Asthenia (22%),Constipation (22%),Pelvic pain (21%),Infection (18%),Nausea (15%),Dyspnea (13%),Edema (13%),Peripheral edema (13%),Diarrhea (12%),Hematuria (12%),Nocturia (12%),Abdominal pain (11%),Anemia (11%) 1-10% Gynecomastia (9%),Rash (9%),UTI (9%),Chest pain (8%),Hypertension (8%),Vomiting (8%),Flu like symptoms (7%),Headache (7%),LFTs elevation (7%),Weight loss (7%),Anorexia (6%),Breast pain (6%),Anxiety (5%) Arthritis (5%)

Mechanism of Action

Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin, thus preventing the growth of normal and malignant prostatic tissue.

Note

Bypro 50mg Tablet manufactured by Fresenius Kabi pharmaceuticals. Its generic name is Bicalutamide. Bypro is availble in Nepal. Farmaco Nepal drug index information on Bypro Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Bicalutamide :