Calcium Tablet

Calcium Gluconate
250mg
Novartis India Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 86.48 NPR

Available as:

Indications

Calcium Tablet is used for: Postmenopausal osteoporosis, Osteoporosis, Hypoparathyroidism, Latent tetany, Rickets, Osteomalacia, Hyperkalemia, Hypocalcemia, Magnesium sulfate overdose

Adult Dose

Hypocalcemia Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism) Mild (ionized calcium 1-1.2 mmol/L) Management of non-life-threatening symptoms IV: 1-2 g over 2 hours Severe (ionized calcium <1 mmol/L) Without seizure or tetany: 0.5 mg/kg/hr IV; may be increased to 2 mg/kg/hr; not to exceed 3-4 g IV over 4 hours Hypocalcemic tetany: 100-300 mg elemental calcium (~3 g calcium gluconate) IV over 5-10 minutes, followed by continuous IV infusion at 0.5 mg/kg/hr (may be increased to 2 mg/kg/hr) Monitor serum calcium q4-6hr to maintain serum calcium levels

Child Dose

Hypocalcemia Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism) Severe Neonates: 200-800 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions Infants/children: 200-500 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions Hypocalcemic tetany 100-200 mg/kg IV over 10 minutes; may be repeated after 6 hours, or initiate continuous infusion not to exceed 500 mg/kg/day

Renal Dose

Administration

Contra Indications

Patients with calcium renal calculi or history of renal calculi. Conditions associated with hypercalcaemia and hypercalciuria.

Precautions

Impaired renal function; cardiac disease; hypercalcaemia-associated diseases, e.g. sarcoidosis; other malignancies. Pregnancy. Lactation: Calcium enters human milk; use with caution

Pregnancy-Lactation

Interactions

Calcium Gluconate: Co-admin of high calcium doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vitamin D metabolite).

Adverse Effects

Side effects of Calcium Gluconate : Bradycardia,Hypotension,Headache,Constipation,Diarrhea,Flatulence,Nausea,Vomiting,Hypomagnesemia,Hypophosphatemia,Extravasation necrosis Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation. Potentially Fatal: Cardiac arrhythmias and coma.

Mechanism of Action

Calcium gluconate/lactate is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.

Note

Calcium 250mg Tablet manufactured by Novartis India Ltd.. Its generic name is Calcium Gluconate. Calcium is availble in Nepal. Farmaco Nepal drug index information on Calcium Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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