Clinace Ointment
Clindamycin 1%
1% W/V
Maruti Pharma Pvt. Ltd.
| Pack size | 15g |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 110.00 NPR |
Indications
Clinace Ointment is used for:
Acne vulgaris, erythrasma, rosacea, periorificial dermatitis, folliculitis, stasis, chronic lymphaedema and familial pemphigus, dermal ulcers.
Adult Dose
Topical/Cutaneous
Acne
Adult: As 1% preparation: Apply a thin layer onto affected area bid.
Child Dose
<12 years old
Safety and efficacy not established
>12 years: Apply a thin layer onto affected area bid.
Renal Dose
Administration
Contra Indications
Contraindicated in patients with hypersensitivity to clindamycin.
Precautions
It is not for oral, ophthalmic, or Intravaginal use.
Avoid exposure to sunlight and sunlamps. Wear sunscreen daily.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Interactions
May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).
Adverse Effects
Side effects of Clindamycin 1% :
>10%
Dryness (18-23%),Oiliness (1-18%),Erythema (7-16%),Peeling (7-11%),Burning/itching (6-11%)
1-10%
Headache (3%)
Mechanism of Action
Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting to stunted cell growth. May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).
Note
Clinace 1% W/V Ointment manufactured by Maruti Pharma Pvt. Ltd.. Its generic name is Clindamycin 1%. Clinace is availble in Nepal.
Farmaco Nepal drug index information on Clinace Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.