Clomigen Cream
Beclomethasone dipropionate 0.025% + Gentamycin 0.1% Topical
0.025% + 0.1%
Deurali Janta Pharmaceuticals Pvt. Ltd.
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| Retail Price | 50.00 NPR |
Indications
Clomigen Cream is used for:
Corticosteroid responsive dermatoses, Psoriasis, Eczema, Contact dermatitis
Adult Dose
Adult: Apply to the affected area 2-3 times daily.
Child Dose
Child> 1 year: Apply to the affected area 3-4 times daily.
Renal Dose
Administration
Contra Indications
History of hypersensitivity to aminoglycoside; pregnancy; hepatic impairment, skin rash.
Precautions
Chronic topical corticosteroid therapy may interfere with growth and development in children
Prolonged treatment with corticosteroids is associated with Kaposi sarcoma (consider discontinuation of therapy if diagnosed)
Discontinue if contact dermatitis occurs; not for use in patients with decreased skin circulation
Manifestations of Cushing syndrome, hyperglycemia, or glycosuria occur, especially if occlusive dressings are used
Prolonged use may result in bacterial or fungal superinfection; discontinue if super infection develops
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Beclomethasone dipropionate 0.025% + Gentamycin 0.1% Topical :
Skin atrophy,Striae,Burning,Dry skin,Erythema folliculitis,Hypertrichosis,Irritation,Miliaria,Vesiculation,Acneform lesions,Pigmentation changes,Allergic contact dermatitis, Erythema, Pruritus
Mechanism of Action
Beclomethasone is a corticosteroid that has anti-inflammatory activity. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes, inhibiting macrophage accumulation in inflamed areas, reducing leukocyte adhesion to capillary endothelium, reducing capillary wall permeability and edema formation, decreasing complement components, antagonizing histamine activity and release of kinin from substrates, and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation
Gentamicin is an aminoglycoside that has broad spectrum bactericidal activity; it is active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
Note
Clomigen 0.025% + 0.1% Cream manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Beclomethasone dipropionate 0.025% + Gentamycin 0.1% Topical. Clomigen is availble in Nepal.
Farmaco Nepal drug index information on Clomigen Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.