Coverit Solution

Minoxidil Topical
5% w/v
Micro Labs Ltd.
Pack size 60ml
Dispensing mode
Source
Agent
Retail Price 1000.00 NPR

Indications

Coverit Solution is used for: Male pattern baldness, Alopecia androgenetica

Adult Dose

Androgenetic Alopecia Male: Apply 1 mL of 2% or 5% solution to affected areas of scalp BID; no more than 2 ml in 24 hours Female: Apply 1 mL of 2% solution to affected areas of scalp BID It should be used twice daily for four months or more before evidence of hair growth can be expected.

Child Dose

<18 years old: Safety & efficacy not established

Renal Dose

Administration

Hair and scalp should be thoroughly dry prior to topical application of Minoxidil. A dose of 1 ml Minoxidil cutaneous solution should be applied to the total affected areas of the scalp twice daily. The total dosage should not exceed 2 ml. If fingertips are used to facilitate drug application, hands should be washed afterwards.

Contra Indications

Minoxidil topical solution is contraindicated in patients with a history of hypersensitivity to Minoxidil or any of the other ingredients in the formulation such as propylene glycol or ethanol.

Precautions

Before using Minoxidil, the user should determine that the scalp is normal and healthy. Patients with known cardiovascular disease or cardiac arrhythmia should contact a physician before using Minoxidil. Minoxidil contains alcohol, which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin and mucous membranes) the area should be bathed with large amount of cool tap water. Lactation: following topical application of the drug is not known, but the drug has been shown to distribute into milk following oral administration in lactating women

Pregnancy-Lactation

Interactions

Topical: Absorption may be increased with corticosteroids, retinoids, occlusive ointment bases. Potentially Fatal: Severe orthostatic hypotension may occur with guanethidine.

Adverse Effects

Side effects of Minoxidil Topical : 1-10% Allergic contact dermatitis (7.4%),Tendonitis (2.6%) Frequency Not Defined Irritation,Burning,Erythema at site of application,May see systemic effects (hypotension)

Mechanism of Action

Minoxidil is an antihypertensive with direct vasodilating property. It reduces elevated BP accompanied by reflex tachycardia, increased cardiac output and elevated plasma renin. Applied topically, minoxidil stimulates hair growth secondary to vasodilation, increases cutaneous blood flow and stimulates resting hair follicles.

Note

Coverit 5% w/v Solution manufactured by Micro Labs Ltd.. Its generic name is Minoxidil Topical. Coverit is availble in Nepal. Farmaco Nepal drug index information on Coverit Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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