CTZ Syrup
Cetirizine
5mg
Nepal Pharmaceuticals Pvt. Ltd.
| Pack size | 5ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 40.00 NPR |
Available as:
Indications
CTZ Syrup is used for:
Allergic rhinitis, Hay fever, Allergies, Urticaria
Adult Dose
Oral
Allergic conditions
Adult: 10 mg once daily or 5 mg bid.
Elderly: Initially, 5 mg once daily.
Hepatic impairment: Initially, 5 mg once daily.
Syrup:
Adults: 2 teaspoon once daily or 1 teaspoon twice daily.
Child Dose
Oral
Allergic conditions
Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses.
Syrup:
Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily.
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily.
<2 years: Safety and efficacy not established
Renal Dose
Renal impairment
GFR >50 mL/min: Dose adjustment not necessary
GFR ? 50 mL/min: 5 mg PO qDay
Peritoneal dialysis: 5 mg PO qDay
Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity; lactation.
Precautions
Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy.
Lactation: Excreted in breast milk; use not recommended
Pregnancy-Lactation
Interactions
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
Adverse Effects
Side effects of Cetirizine :
>10%
Somnolence (2-14%),Headache (11-14%)
1-10%
Fatigue (5.9%),Dry mouth (5%),Dizziness (2%),Diarrhea (2-3%),Malaise (4%),Bronchospasm (2-3%),Vomiting (2-3%),Epistaxis (2-4%)
<1%
Stomach pain,Drowsiness,Angioedema,Fussiness,Hallucinations,Hypotension,Tremor,Tongue discoloration
Mechanism of Action
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Note
CTZ 5mg Syrup manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Cetirizine. CTZ is availble in Nepal.
Farmaco Nepal drug index information on CTZ Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.