Cyclomune Eye Drop
Cyclosporine 0.05% Eye prep
Sun Pharmaceutical Industries Ltd.
| Pack size | 3ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 440.00 NPR |
Indications
Cyclomune Eye Drop is used for:
Dry eye
Adult Dose
Keratoconjuntivitis Sicca
1 drop twice daily approximately 12 hours apart in each eye
May be used with artificial tears; allow 15-minute interval between products
Child Dose
<16 years
Safety and efficacy not established
>16 years
Keratoconjuntivitis Sicca
1 drop twice daily approximately 12 hours apart in each eye
May be used with artificial tears; allow 15-minute interval between products
Renal Dose
Administration
Contra Indications
Cyclosporine is contraindicated in patients with active ocular infections and in patients with known or suspected hypersensitivity to any of the ingredients in the formulation.
Precautions
Cyclosporine eye drop should not be administered while wearing contact lenses. Patients with decreased tear production typically should not wear contact lenses. If contact lenses are worn, they should be removed prior to the administration of this formulation. Lenses may be reinserted 15 minutes following administration of Cyclosporine eye drop.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Interactions
Increased ciclosporin level by diltiazem, doxycycline, erythromycin, ketoconazole, methylprednisolone (high doses), nicardipine, verapamil, oral contraceptives. Drugs which reduce ciclosporin level are carbamazepine, isoniazid, phenobarbitone, phenytoin and rifampicin. Increased risk of convulsion when used concurrently with high-dose methylprednisolone.
Potentially Fatal: Additive nephrotoxicity when used with aminoglycosides, amphotericin B, ciprofloxacin, colchicine, melphalan, co-trimoxazole and NSAIDs.
Adverse Effects
Side effects of Cyclosporine 0.05% Eye prep :
>10%
Ocular burning (17%)
Frequency Not Defined
Conjunctival hyperemia,Discharge,Epiphora,Eye pain,Foreign body sensation,Pruritus
Mechanism of Action
Ciclosporin is a strong immunosuppressant that acts mainly on the helper T-cells. It inhibits the activation of calcineurin and production of interleukin-2, thus reducing cell-mediated immune response. May act as immunomodulator to suppress tear production in keratoconjunctivitis sicca
Note
Cyclomune Eye Drop manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Cyclosporine 0.05% Eye prep. Cyclomune is availble in Nepal.
Farmaco Nepal drug index information on Cyclomune Eye Drop is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.