Cytomid Tablet
Flutamide
250mg
Cipla Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 14.48 NPR |
Indications
Cytomid Tablet is used for:
Prostate cancer
Adult Dose
Oral
Palliative treatment of prostatic carcinoma
Adult: 250 mg tid preferably at least 3 days before gonadorelin analogue treatment.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Precautions
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease.
Lactation: Excretion in milk unknown; not recommended
Pregnancy-Lactation
Interactions
Increased prothrombin time in patients on long-term warfarin treatment.
Adverse Effects
Side effects of Flutamide :
>10%
Hot flashes (61%),Decreased libido (36%),Impotence (31%),Diarrhea (12%),Nausea/vomiting (11%)
1-10%
Gynecomastia (9%),Anorexia (4%),Edema (4%),Leukopenia (3%),Rash (3%)
Frequency Not Defined
Hemolytic anemia, methemoglobinemia
Increased AST, ALT, bilirubin, BUN
Mechanism of Action
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
Note
Cytomid 250mg Tablet manufactured by Cipla Ltd.. Its generic name is Flutamide. Cytomid is availble in Nepal.
Farmaco Nepal drug index information on Cytomid Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.