Dart Tablet
Dutasteride
0.5mg
Quest Pharmaceuticals Pvt. Ltd.
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| Retail Price | 22.00 NPR |
Indications
Dart Tablet is used for:
Benign prostatic hyperplasia (BPH)
Adult Dose
Oral
Benign prostatic hyperplasia
Adult: 500 mcg once daily for at least 6 mth.
Hepatic impairment: Severe: Contraindicated.
Child Dose
Renal Dose
Renal impairment: Dose adjustment not necessary
Administration
May be taken with or without food.
Contra Indications
Severe liver impairment; pregnant women, children, adolescent.
Precautions
Excreted in semen therefore use of condom is recommended. Women of childbearing potential should avoid handling dutasteride capsules. Advisable to exclude other causes of benign prostatic hypertrophy (e.g. prostate cancer, infection) before initiating therapy.
Lactation: Excretion in milk unknown/contraindicated
Pregnancy-Lactation
Interactions
Plasma concentrations may be increased when used concomitantly w/ moderate or potent CYP3A4 inhibitors.
Adverse Effects
Side effects of Dutasteride :
1-10%
Impotence,Decreased libido,Ejaculation disorder,Breast disorders/gynecomastia
<1%
Dizziness
Frequency Not Defined
Cardiac failure,Prostate cancer (high grade)
Mechanism of Action
Dutasteride has antiandrogenic properties. It inhibits 5alpha-reductase, thus preventing the conversion of testosterone to 5?-dihydrotestosterone which is the main androgen involved in causing prostate enlargement.
Note
Dart 0.5mg Tablet manufactured by Quest Pharmaceuticals Pvt. Ltd.. Its generic name is Dutasteride. Dart is availble in Nepal.
Farmaco Nepal drug index information on Dart Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.