Denovo Syrup
Elemental Iron + Folic Acid + Zinc + Vitamin B12
Nepal Pharmaceuticals Pvt. Ltd.
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| Retail Price | 70.01 NPR |
Indications
Denovo Syrup is used for:
Iron, Vitamin-B, Zinc deficiency
Adult Dose
Oral
Adults: 10 ml (2 teaspoonful) twice daily
Child Dose
Children: 5 ml (1 teaspoonful) once or twice daily
Infants: 0.33 ml/Kg body weight daily
Renal Dose
Administration
Contra Indications
Patients with a known hypersensitivity to any of the ingredients of this product. Iron compounds are contraindicated in patients with hemosiderosis, hemochromatosis, and hemolytic anemias.
Precautions
Caution should be taken in the conditions where there is a risk of iron overload, such as haemochromatosis, thalassemia, haemosiderosis or haemolytic anaemia.
Pregnancy-Lactation
Interactions
Iron: Absorption decreased w/ antacids. May reduce effects of penicillamine. Concurrent use with psychotropic drugs may worsen constipation. Increased systemic side effects with concomitant ACE inhibitors and parenteral iron admin.
Adverse Effects
Side effects of Elemental Iron + Folic Acid + Zinc + Vitamin B12 :
A few side-effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur.
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Zinc: Cofactor in over 100 enzymes; plays a role in DNA synthesis; supports a healthy immune system; helps maintain a sense of smell and taste; may assist in porper function of insulin.
Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increaase chylomicron triglyceride removal from plasma. Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erthropoiesis, nucleprotein and myelin synthesis, cell reproduction and normal growth; intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of Vitamin B12 from the GI tract. Necessary for normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin.
Note
Denovo Syrup manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Elemental Iron + Folic Acid + Zinc + Vitamin B12. Denovo is availble in Nepal.
Farmaco Nepal drug index information on Denovo Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.