Diplene Cream

Betamethasone valerate 0.05% Topical
0.005%
Fulford India Ltd.
Pack size 10gm
Dispensing mode
Source
Agent
Retail Price 147.02 NPR

Indications

Diplene Cream is used for: Eczema, atopic dermatitis, contact dermatitis, , systemic lupus erythematosus, lichen planus, lichen simplex, psoriasis, prurigo nodularis, plaque psoriasis

Adult Dose

As valerate: Apply sparingly 2-3 times daily. Cream for moist & ointment for dry surface.

Child Dose

Renal Dose

Administration

Topical Administration Use medium to very high potency for less than 2 weeks to reduce local and systemic side effects Use low potency for chronic therapy Avoid medium to very high potency on face, folds, and groin, because use in these areas can increase steroid absorption Use lower potency for children (ie, increased BSA/kg, therefore increased systemic absorption)

Contra Indications

Underlying infection, Hypersensitivity, Ophthalmic use

Precautions

Chronic topical corticosteroid therapy may interfere with growth and development in children. Lactation: It is not known whether topical corticosteroid use could result in sufficient systemic absorption to produce detectable quantities in human milk; use with caution.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Betamethasone valerate 0.05% Topical : Dermal atrophy, local irritation, folliculitis, hypertrichosis, burning, dry skin, pigmentation changes, HPA suppression (with higher potency used >2 wk)

Mechanism of Action

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.

Note

Diplene 0.005% Cream manufactured by Fulford India Ltd.. Its generic name is Betamethasone valerate 0.05% Topical. Diplene is availble in Nepal. Farmaco Nepal drug index information on Diplene Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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