Doxolin Tablet
Doxofylline
400mg
Nepal Pharmaceuticals Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 7.00 NPR |
Indications
Doxolin Tablet is used for:
COPD (Chronic Obstructive Pulmonary Disease) and bronchial asthma
Adult Dose
Adults: 200-400 mg tablet: 1 to 3 times a day.
Up to 1200 mg daily.
Dosage of Doxofylline depends on patient’s response to the medication.
If a patient has been advised to dose once a day, he or she may be directed to do so in the evenings to reduce nocturnal symptoms.
Elderly: The dosage may be decreased according to medical prescription in the very elderly patients with concomitant cardiovascular, hepatic, renal and gastric disease,
200 mg 2 or 3 times daily.
Child Dose
Children >12 years: 200 mg 2 or 3 times daily.
Renal Dose
Administration
Contra Indications
This is contraindicated for individuals who have shown hypersensitivity to Doxofylline and its components. It is also contraindicated in patients with acute myocardial infarction, hypotension, and in lactating women.
Precautions
Use with caution in patients with hypoxemia, hyperthyroidism, liver disease, renal disease, in those with history of peptic ulcer and in elderly. Frequently, patients with Congestive Heart Failure (CHF) have markedly prolonged drug serum levels following discontinuation of Doxofylline.
Pregnancy-Lactation
Interactions
Other xanthine derivatives, ephedrine, phenytoin & other anticonvulsants, erythromycin, troleandomycin, lincomycin, clindamycin, allopurinol, cimetidine, ranitidine, propranolol, flu vaccine.
Adverse Effects
Side effects of Doxofylline :
After xanthine administration, nausea, vomiting, epigastric pain, cephalalgia, irritability, insomnia, tachycardia, extrasystole, tachypnea and occasionally, hyperglycemia and albuminuria, may occur. If a potential oral overdose is established, the patient may present with severe arrhythmias and seizure; these symptoms could be the first sign of an intoxication. Adverse reactions may cause the withdrawal from treatment; a lower dose rechallenge may start only after the advice of a physician.
Mechanism of Action
Doxofylline is a theophylline derivative. Similarly, its mechanism of action is related to the inhibition of phosphodiesterase activities, resulting in bronchodilating effects.
Note
Doxolin 400mg Tablet manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Doxofylline. Doxolin is availble in Nepal.
Farmaco Nepal drug index information on Doxolin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.