Drota 40 Tablet

Drotaverine Hydrochloride
40mg
Apex Pharmaceuticals Pvt. Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price

Available as:

Indications

Drota 40 Tablet is used for: Gastrointestinal tract spasm, Irritable bowel syndrome, Dysmenorrhea, Biliary colics, Renal colics

Adult Dose

Oral As an antispasmodic Adult: 1 to 2 tablets, 3 times daily. Injection: Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily. For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.

Child Dose

Oral As an antispasmodic Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily. 40 mg 1-2 times daily Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily. 20 mg 1-2 times daily

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Severe renal/hepatic/cardiac dysfunction. Porphyria.

Precautions

Exercise caution in patients with renal/hepatic/cardiac dysfunction. Pregnacy, lactation.

Pregnancy-Lactation

Interactions

May attenuate the action of levodopa. Concurrent use of analgesics, antimuscarinics or benzodiazepines. Additive beneficial effect with concurrent use of analgesics, antimuscarinics or benzodiazepines.

Adverse Effects

Side effects of Drotaverine Hydrochloride : Vertigo, nausea, vomiting, dry mouth.

Mechanism of Action

Drotaverine has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.

Note

Drota 40 40mg Tablet manufactured by Apex Pharmaceuticals Pvt. Ltd.. Its generic name is Drotaverine Hydrochloride. Drota 40 is availble in Nepal. Farmaco Nepal drug index information on Drota 40 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Drotaverine Hydrochloride :