Drotin Injection
Drotaverine Hydrochloride
40mg
Walter Bushnell
| Pack size | 1's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 34.29 NPR |
Available as:
Indications
Drotin Injection is used for:
Gastrointestinal tract spasm, Irritable bowel syndrome, Dysmenorrhea, Biliary colics, Renal colics
Adult Dose
Oral
As an antispasmodic
Adult: 1 to 2 tablets, 3 times daily.
Injection: Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily.
For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.
Child Dose
Oral
As an antispasmodic
Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily.
40 mg 1-2 times daily
Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily.
20 mg 1-2 times daily
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Severe renal/hepatic/cardiac dysfunction. Porphyria.
Precautions
Exercise caution in patients with renal/hepatic/cardiac dysfunction. Pregnacy, lactation.
Pregnancy-Lactation
Interactions
May attenuate the action of levodopa. Concurrent use of analgesics, antimuscarinics or benzodiazepines. Additive beneficial effect with concurrent use of analgesics, antimuscarinics or benzodiazepines.
Adverse Effects
Side effects of Drotaverine Hydrochloride :
Vertigo, nausea, vomiting, dry mouth.
Mechanism of Action
Drotaverine has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.
Note
Drotin 40mg Injection manufactured by Walter Bushnell. Its generic name is Drotaverine Hydrochloride. Drotin is availble in Nepal.
Farmaco Nepal drug index information on Drotin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.