Duphaston Tablet

Dydrogesterone
10mg
Abbott India Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 88.93 NPR

Indications

Duphaston Tablet is used for: Endometriosis, Miscarriage, Menstrual disorders, Infertility, Dysmenorrhea, Dysfunctional uterine bleeding, Premenstrual syndrome, Hormone replacement therapy

Adult Dose

Oral Endometriosis Adult: 10 mg bid-tid cyclically or continuously. Recurrent miscarriage Adult: 10 mg bid given cyclically until conception, then continuously until wk 20 of pregnancy, after which dose may be gradually reduced. Menstrual disorders Adult: 10 mg bid in a cyclical regimen. Threatened miscarriage Adult: Initially, 40 mg followed by 10 mg or more every 8 hr, continued for a wk after symptoms are relieved. Reduce dose gradually after that unless symptoms return. Infertility Adult: 10 mg bid. Endometrial protection during menopausal hormonal replacement therapy Adult: 10 mg 1-2 times daily in a cyclical regimen or 5 mg daily.

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity; pregnancy. Undiagnosed abnormal vag bleeding, thromboembolic disorders, history or existing cerebrovascular or coronary artery disease, missed or incomplete abortion, known or suspected carcinoma of the breast or genital organs, severe hepatic dysfunction, as a diagnostic test for pregnancy.

Precautions

Monitor closely for loss of vision, proptosis, diplopia, migraine, signs and symptoms of embolic disorders. CVD or renal impairment, epilepsy, asthma, other conditions which may be aggravated by fluid retention. Lactation.

Pregnancy-Lactation

Interactions

Carbamazepine, griseofulvin, phenobarbital, rifampicin enhances the clearance of progestogens.

Adverse Effects

Side effects of Dydrogesterone : Dizziness, nausea, headache, fatigue, emotional lability, irritability; abdominal pain and distention; muskuloskeletal pain.

Mechanism of Action

Dydrogesterone is a progestogen structurally related to progesterone. However, unlike progesterone, it does not induce an increase in temp nor inhibit ovulation and may be preferred over other progestational agents when contraceptive effect is not required. It does not have oestrogenic or androgenic properties.

Note

Duphaston 10mg Tablet manufactured by Abbott India Ltd.. Its generic name is Dydrogesterone. Duphaston is availble in Nepal. Farmaco Nepal drug index information on Duphaston Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Dydrogesterone :