Duphaston Tablet
Dydrogesterone
10mg
Abbott India Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 88.93 NPR |
Indications
Duphaston Tablet is used for:
Endometriosis, Miscarriage, Menstrual disorders, Infertility, Dysmenorrhea, Dysfunctional uterine bleeding, Premenstrual syndrome, Hormone replacement therapy
Adult Dose
Oral
Endometriosis
Adult: 10 mg bid-tid cyclically or continuously.
Recurrent miscarriage
Adult: 10 mg bid given cyclically until conception, then continuously until wk 20 of pregnancy, after which dose may be gradually reduced.
Menstrual disorders
Adult: 10 mg bid in a cyclical regimen.
Threatened miscarriage
Adult: Initially, 40 mg followed by 10 mg or more every 8 hr, continued for a wk after symptoms are relieved. Reduce dose gradually after that unless symptoms return.
Infertility
Adult: 10 mg bid.
Endometrial protection during menopausal hormonal replacement therapy
Adult: 10 mg 1-2 times daily in a cyclical regimen or 5 mg daily.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity; pregnancy. Undiagnosed abnormal vag bleeding, thromboembolic disorders, history or existing cerebrovascular or coronary artery disease, missed or incomplete abortion, known or suspected carcinoma of the breast or genital organs, severe hepatic dysfunction, as a diagnostic test for pregnancy.
Precautions
Monitor closely for loss of vision, proptosis, diplopia, migraine, signs and symptoms of embolic disorders. CVD or renal impairment, epilepsy, asthma, other conditions which may be aggravated by fluid retention. Lactation.
Pregnancy-Lactation
Interactions
Carbamazepine, griseofulvin, phenobarbital, rifampicin enhances the clearance of progestogens.
Adverse Effects
Side effects of Dydrogesterone :
Dizziness, nausea, headache, fatigue, emotional lability, irritability; abdominal pain and distention; muskuloskeletal pain.
Mechanism of Action
Dydrogesterone is a progestogen structurally related to progesterone. However, unlike progesterone, it does not induce an increase in temp nor inhibit ovulation and may be preferred over other progestational agents when contraceptive effect is not required. It does not have oestrogenic or androgenic properties.
Note
Duphaston 10mg Tablet manufactured by Abbott India Ltd.. Its generic name is Dydrogesterone. Duphaston is availble in Nepal.
Farmaco Nepal drug index information on Duphaston Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.