Efelin Tablet

Salbutamol + Bromhexine
2mg +8mg+ 200mg
Indoco Remedies Ltd.
Pack size 10's
Dispensing mode
Source
Agent
Retail Price 0.59 NPR

Indications

Efelin Tablet is used for: Bronchial asthma, emphysema, atelectasis, acute/chronic bronchitis, pulmonary TB, whooping cough, pneumonia & other broncho-spastic conditons.

Adult Dose

Oral Adult 2 tsf tid.

Child Dose

Oral Childn 6-12 yr 1-2 tsf tid, <6 yr 1 tsf tid.

Renal Dose

Administration

Should be taken with food.

Contra Indications

Hypersensitivity

Precautions

Patients w/ hyperthyroidism, DM, serious CV disorders, HTN & peptic ulcer. Pregnancy & lactation.

Pregnancy-Lactation

Interactions

Diuretics, MAOIs, digoxin.

Adverse Effects

Side effects of Salbutamol + Bromhexine : Skeletal muscle tremor of the hands, palpitations, muscle cramps. Slight tachycardia, headache & peripheral vasodilation at large doses.

Mechanism of Action

Salbutamol activates adenyl cyclase, the enzyme that stimulates the production of cyclic adenosine-3', 5'-monophosphate (cAMP). Increased cAMP leads to activation of protein kinase A, which inhibits phosphorylation of myosin and lowers intracellular ionic Ca concentrations, resulting in smooth muscle relaxation. Bromhexine enhances mucus transport by reducing mucus viscosity and by activating the ciliated epithelium (mucociliary clearance).

Note

Efelin 2mg +8mg+ 200mg Tablet manufactured by Indoco Remedies Ltd.. Its generic name is Salbutamol + Bromhexine. Efelin is availble in Nepal. Farmaco Nepal drug index information on Efelin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Salbutamol + Bromhexine :