Eldoper Plus Tablet
Loperamide + Simethicone
Micro Labs Ltd.
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Indications
Eldoper Plus Tablet is used for:
Diarrhea, Flatulence
Adult Dose
Adult
Diarrhea/Flatulence
After each loose bowel movement: 2 tablets once initially, then 1 tab/dose with each subsequent loose stool up to 4 tab/day
Child Dose
Child
Diarrhea/Flatulence
<6 years: Safety and efficacy not established
6-8 years: 1 tablet once initially, then one-half tablet/dose, up to 2 tablets/day
9-12 years: 1 tablet once initially, then one-half tablet/dose, up to 3 tablets/day
> 12 years: After each loose bowel movement: 2 tablets once initially, then 1 tab/dose with each subsequent loose stool up to 4 tab/day
Renal Dose
Administration
Contra Indications
Hypersensitivity, bloody diarrhea, high fever, infectious diarrhea, pseudomembranous colitis
Patients in whom constipation must be avoided
Abdominal pain without diarrhea
Avoid use as primary therapy with acute dysentery (bloody stools and high fever, acute ulcerative colitis, bacterial enterocolitis [caused by Salmonella, Shigella, and Campylobacter), pseudomembranous colitis associated with antibiotic use)
Age <2 years
Precautions
loperamide
May cause drowsiness or dizziness, which may impair physical abilities to operate heavy machinery or tasks requiring mental alertness
Hypersensitivity reactions reported, including anaphylaxis, rash, urticaria, and rare cases of Steven’s Johnson syndrome or toxic epidermal necrolysis
Discontinue if no improvement seen within 48 hr in patients with acute diarrhea, symptoms worsen, or abdominal swelling or bulging develops
Discontinue promptly if constipation, abdominal pain or distention, blood in stool, or ileus develops; do not use when peristalsis inhibition should be avoided (ie, due to potential for ileus, megacolon, or toxic megacolon)
Discontinue therapy if symptoms of abdominal distention occur in patients with AIDS; cases of toxic megacolon reported with infectious colitis, resulting from viral or bacterial pathogens
simethicone
Can cause false-negative gastric guaiac test
Lactation: Unknown if distributed in to breast milk, use caution
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Loperamide + Simethicone :
Frequency Not Defined
Dizziness
Fatigue
Headache
Abdominal pain
Dry mouth
Nausea
Diarrhea
Vomiting
Pancreatitis
Mechanism of Action
Slows intestinal motility by direct effects on circular & longitudinal muscle (loperamide); changes surface tension of gas bubbles, causing collapse of foam bubbles, thus allow easier passage (simethicone)
Note
Eldoper Plus Tablet manufactured by Micro Labs Ltd.. Its generic name is Loperamide + Simethicone. Eldoper Plus is availble in Nepal.
Farmaco Nepal drug index information on Eldoper Plus Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.