Enkephal Capsule
Racecadotril
100mg
QbD Pharmaceuticals
| Pack size | 10's pack |
|---|---|
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| Retail Price |
Indications
Enkephal Capsule is used for:
Acute diarrhoea
Adult Dose
Oral
Acute diarrhoea
Adult: 100 mg tid. Continue treatment until 2 normal stools are recorded. Max duration: 7 days.
Child Dose
Oral
Acute diarrhoea
Child: 3 mth to 17 yr <9 kg: 10 mg tid;
9 to <13 kg: 20 mg tid;
13-27 kg: 30 mg tid;
>27 kg: 60 mg tid.
Continue treatment until 2 normal stools are recorded.
Max duration: 7 days.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity to Racecadotril, or to any of the excipients.
Precautions
Chronic & antibiotic-associated diarrhoea, bloddy or purulent stools & fever, patients w/ diabetes, renal or liver impairment, cases of prolonged or uncontrolled vomiting. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Racecadotril :
Headache, tonsillitis, rash, erythema multiforme or nodosum; tongue, face, lip or eyelid oedema; angioedema, urticaria, prurigo, pruritus.
Mechanism of Action
Racecadotril increases the availability of endogenous opioids (enkephalins) by inhibiting the membrane-bound enkephalinase. These enkephalins activate delta-opioid receptors in the GI tract. This leads to a reduction in cAMP mucosal levels, resulting in a reducted secretion of water and electrolytes in the intestinal lumen.
Note
Enkephal 100mg Capsule manufactured by QbD Pharmaceuticals. Its generic name is Racecadotril. Enkephal is availble in Nepal.
Farmaco Nepal drug index information on Enkephal Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.