Fenolip Tablet

Fenofibrate
145mg
Cipla Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 23.36 NPR

Indications

Fenolip Tablet is used for: Hyperlipidemia,Hypercholesterolaemia,Hypertriglyceridaemia

Adult Dose

Oral Hypercholesterolemia, Mixed dyslipidemia, Hypertriglyceridemia Tablet: 40-160mg once daily. Capsule: 200mg once daily. Hepatic impairment: Contraindicated.

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment Mild-Moderate: Initial: lower dose Severe: contraindicated

Administration

Should be taken with food.

Contra Indications

Hypersensitivity; severe hepatic and renal impairment. Unexplained persistent liver function abnormality and primary biliary cirrhosis; preexisting gall bladder disease. Pregnancy, lactation.

Precautions

Renal or hepatic impairment. Monitor LFTs and blood counts regularly. Increased risk of cholelithiasis, pancreatitis, skeletal muscle effects. Withdraw treatment if no adequate response after 2 mth of treatment at max recommended dose. Lactation: Unknown if excreted in breast milk; not recommended

Pregnancy-Lactation

Interactions

Decreased absorption w/ bile acid sequestrants (e.g. colestyramine). May increase risk of ciclosporin-induced nephrotoxicity. Increased risk of muscle toxicity w/ HMG-CoA reductase inhibitors (e.g. simvastatin). May increase risk of bleeding w/ oral anticoagulants.

Adverse Effects

Side effects of Fenofibrate : 1-10% Abdominal pain (4.6%),Back pain (3.4%),Increased AST (3.4%),Headache (3.2%),Increased ALT (3%),Increased CPK (3%),Nausea (2.3%),Constipation (2.1%) Potentially Fatal: Hepatitis, cholecystitis.

Mechanism of Action

Fenofibrate, a fibric acid derivative, lowers plasma triglyceride by activating lipoprotein lipase thus increasing catabolism of VLDL w/ consequent increase in HDL levels.

Note

Fenolip 145mg Tablet manufactured by Cipla Ltd.. Its generic name is Fenofibrate. Fenolip is availble in Nepal. Farmaco Nepal drug index information on Fenolip Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Fenofibrate :