Flexinol Tablet
Paracetamol + Methocarbamol
325 mg + 400 mg
Cipla Ltd.
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Indications
Flexinol Tablet is used for:
Spasm & pain associated with acute musculoskeletal disorders. Also tension myalgia, acute traumatic muscle spasm, acute disc prolapse, painful shoulder syndrome. Post-operative joint pain & mechanical low back pain.
Adult Dose
Adult & child over 12 yrs: 1-2 tabs tid;
Child Dose
Child under 12 yrs: not recommended.
Renal Dose
Administration
May be taken w/ meals to reduce GI discomfort.
Contra Indications
Coma or pre-coma states, brain damage, myasthenia gravis Do not admin parenteral solutions in patients with renal impairment, epilepsy or history of epilepsy.
Precautions
Renal or hepatic impairment; acidosis. Pregnancy and lactation. May impair ability to drive or operate machinery.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Paracetamol + Methocarbamol :
Nausea, anorexia, lassitude, drowsiness, dizziness, restlesness, anxiety, confusion, fever, headache, blurred vision, convulsions; hypersensitivity reactions e.g. rashes, pruritus, urticaria, angiodema. Parenteral: Flushing and a metallic taste; incoordination, diplopia, nystagmus, vertigo; sloughing and thrombophloebitis at the site of inj. Thrombocytopenia, leucopenia, pancytopenia, neutropenia, agranulocytosis, pain and burning sensation at inj site. Rarely, hypotension and tachycardia.
Potentially Fatal: Parenteral: Syncope, hypotension, bradycardia, anaphylaxis.
Mechanism of Action
Methocarbamol is a centrally acting skeletal muscle relaxant whose precise mode of action is not known. It is said to cause general depression of the central nervous system.
Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS.
Note
Flexinol 325 mg + 400 mg Tablet manufactured by Cipla Ltd.. Its generic name is Paracetamol + Methocarbamol. Flexinol is availble in Nepal.
Farmaco Nepal drug index information on Flexinol Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.