Flucort N Cream

Fluocinolone 0.025% + Neomycin Sulphate 0.5% Topical
0.025% w/w + 0.5% w/w
Glenmark Pharmaceuticals Ltd.
Pack size 20gm
Dispensing mode
Source
Agent
Retail Price 45.58 NPR

Indications

Flucort N Cream is used for: Psoriasis, Eczema, Tularaemia, Dermatitis,

Adult Dose

Adult: Topical cream/oint: Apply 2-3 times/day.

Child Dose

Renal Dose

Administration

Contra Indications

Primary infectious (bacterial, viral, fungal) ulcers, hypersensitivity, acne vulgaris. Neonates.

Precautions

Children, elderly, hepatic failure. Prolonged use on the face; contact with eyes. Pregnancy, lactation.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Fluocinolone 0.025% + Neomycin Sulphate 0.5% Topical : Dry skin, pruritus, irritation, mild to moderate transient burning/stinging. Local atrophic changes in the skin (prolonged & intensive treatment). Hypercorticism (systemic absorption on prolonged use). Itching, folliculitis, hypertrichoses, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of skin, secondary infections, striae & miliaria. Ototoxicity & nephrotoxicity. Prolonged admin causes epidermal thinning, telangiectasia and striae (especially face and flexures). Application on eyelid and surrounding skin can cause raised intraocular pressure, cataracts, glaucoma, corneal ulcers and raised intracranial pressure. Systemic absorption with adrenal suppression may be seen when applied over large areas, when skin is broken or under occlusive dressing.

Mechanism of Action

Fluocinolone acetonide is a synthetic fluorinated corticosteroid that is used topically for its anti-inflammatory, anti-pruritic and vasoconstrictive properties. Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria.

Note

Flucort N 0.025% w/w + 0.5% w/w Cream manufactured by Glenmark Pharmaceuticals Ltd.. Its generic name is Fluocinolone 0.025% + Neomycin Sulphate 0.5% Topical. Flucort N is availble in Nepal. Farmaco Nepal drug index information on Flucort N Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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