Flucreme NM Cream

Fluocinolone + Miconazole + Neomycin Topical
Concept Pharmaceuticals Ltd.
Pack size 10gm
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Indications

Flucreme NM Cream is used for: Allergic inflammatory skin disease (acute & chronic eczema, contact dermatitis, atopic dermatitis, seborrheic dermatitis, chronic simple lichen, intertrigo, exfoliative dermatitis, papular urticaria, psoriasis, pruritus vulvae, pruritus ani, dermatitis solaris; skin mycosis (athlete's foot, trichophytia); tinea versicolor; insect bite and skin disease by secondary bacterial infection.

Adult Dose

Adult: Topical oint: Apply thin film to affected skin areas 2-3 times daily.

Child Dose

Renal Dose

Administration

Contra Indications

Primary infectious (bacterial, viral, fungal) ulcers, hypersensitivity, acne vulgaris. Neonates.

Precautions

Children, elderly, hepatic failure. Prolonged use on the face; contact with eyes. Pregnancy, lactation.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Fluocinolone + Miconazole + Neomycin Topical : Continuous application without interruption may result in local atrophy of the skin, striae and superficial vascular dilation. Rarely, patients may experience local mild burning or irritation.

Mechanism of Action

Fluocinolone acetonide is a synthetic fluorinated corticosteroid that is used topically for its anti-inflammatory, anti-pruritic and vasoconstrictive properties. Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria. Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.

Note

Flucreme NM Cream manufactured by Concept Pharmaceuticals Ltd.. Its generic name is Fluocinolone + Miconazole + Neomycin Topical. Flucreme NM is availble in Nepal. Farmaco Nepal drug index information on Flucreme NM Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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