Indications
Fluothane Solution is used for:
Induction and maintenance of general anaesthesia
Adult Dose
Inhalation
Induction and maintenance of general anaesthesia
Adult: Induction: 0.5% v/v of halothane in oxygen or mixture of nitrous oxide and oxygen, increase gradually according to response to a concentration of 2-4% v/v. Maintenance: 0.5-2% v/v depending on the flow rate used.
Child Dose
Inhalation
Induction and maintenance of general anaesthesia
Child: Induction: 1.5-2% v/v. Maintenance: 0.5-1.5% v/v.
Renal Dose
Administration
Contra Indications
Known or suspected susceptibility to malignant hyperthermia, raised CSF pressure, history of unexplained jaundice or acute hepatic damage from previous exposure to halothane. Childn <18 yr undergoing outpatient dental surgery.
Precautions
Patient w/ phaeochromocytoma, myasthenia gravis, renal failure, pre-existing hepatic disease. Childn. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor pulse and BP.
Pregnancy-Lactation
Interactions
Increased risk of ventricular dysrhythmias w/ epinephrine. Increased risk of malignant hyperthermia w/ suxamethonium. Prolonged recovery from anaesth w/ concurrent use of ketamine for induction. May potentiate response to non-depolarising muscle relaxants, hypotensive agents (e.g. hexamethonium bromide, trimetaphan camsilate).
Adverse Effects
Side effects of Halothane :
Post-op nausea, vomiting, and shivering; resp depression, hypotension, skeletal muscle relaxation, bradycardia.
Potentially Fatal: Hepatotoxicity, malignant hyperthermia, cardiac arrhythmias.
Mechanism of Action
Halothane is a potent non-flammable inhalational anaesth which depresses both cerebral function and sympathetic activity. It suppresses salivary, bronchial and gastric secretions and dilates the bronchioles.
Note
Fluothane Solution manufactured by Abbott India Ltd.. Its generic name is Halothane. Fluothane is availble in Nepal.
Farmaco Nepal drug index information on Fluothane Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.