Fosbait Tablet
Lanthanum Carbonate
500mg
Panacea Biotec Ltd.
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| Retail Price | 1307.38 NPR |
Available as:
Indications
Fosbait Tablet is used for:
Hyperphosphataemia in patients with chronic renal failure
Adult Dose
Oral
Hyperphosphataemia in patients with chronic renal failure
Adult: As chewable tab/oral powd: Initially, 0.75-2.25 g daily in 3 divided doses. Maintenance dose: 1.5-3 g daily in divided doses. Max: 3.75 g daily. Dose is adjusted every 2-3 wk according to serum phosphate level.
Child Dose
Renal Dose
Administration
Should be taken with food. Take w/ or immediately after meals. Chew thoroughly before swallowing. Do not swallow whole.
Contra Indications
Bowel obstruction, ileus, faecal impaction, hyperphosphataemia.
Precautions
Patient w/ altered GI anatomy (e.g. diverticular disease, peritonitis, history of GI surgery, GI cancer, GI ulceration), hypomotility disorders (e.g. constipation, diabetic gastroparesis), active peptic ulcer, Crohn's disease, ulcerative colitis. Hepatic impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness and vertigo, if affected, do not drive or operate machinery. Monitoring Parameters Monitor serum Ca, phosphorus levels.
Pregnancy-Lactation
Interactions
May reduce bioavailability of quinolones, tetracycline and levothyroxine chloroquine, ketoconazole. May decrease serum concentration of ACE inhibitor, ampicillin, halofantrine.
Adverse Effects
Side effects of Lanthanum Carbonate :
Significant: GI obstruction, ileus, subileus, GI perforation, faecal impaction.
Nervous: Headache, dizziness, vertigo, asthenia, fatigue, malaise.
GI: Nausea, vomiting, diarrhoea, abdominal pain, taste alteration, gastroenteritis, constipation, dyspepsia, flatulence, dry mouth, eructation, IBS, anorexia.
Endocrine: Hyperglycaemia, hyperparathyroidism.
Haematologic: Eosinophilia. Musculoskeletal: Bone deposition, arthralgia, myalgia, osteoporosis.
Dermatologic: Alopecia, sweating.
Others: Hypocalcaemia, hyperphosphataemia, hypophosphataemia, hypercalcaemia.
Mechanism of Action
Lanthanum forms strong complexes with PO4 that inhibits GI absorption and results in a decrease of serum phosphate and calcium levels
Note
Fosbait 500mg Tablet manufactured by Panacea Biotec Ltd.. Its generic name is Lanthanum Carbonate. Fosbait is availble in Nepal.
Farmaco Nepal drug index information on Fosbait Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.