Fusigen B Ointment

Fucidic Acid + Betamethasone Topical
Geno Pharmaceuticals Ltd.
Pack size
Dispensing mode
Source
Agent
Retail Price 100.80 NPR

Indications

Fusigen B Ointment is used for: Corticosteriod-responsive dermatoses w/ secondary infection

Adult Dose

Topical/Cutaneous Corticosteriod-responsive dermatoses with secondary infection Adult: Apply to the affected area(s) bid. Max duration: 2 wk.

Child Dose

Renal Dose

Administration

Contra Indications

Skin lesions of viral, fungal or bacterial origin, acne rosacea and perioral dermatitis.

Precautions

Avoid prolonged continuous treatment especially in infants and children. Extended treatment may increase the risk of contact sensitisation and development of antibiotic resistance. Not to be used for >7 days if there is no clinical improvement. Increased risk of glaucoma if preparation enters the eye(s). Pregnancy and lactation.

Pregnancy-Lactation

Interactions

Fucidic Acid: Synergistic action with antistaphylococcal penicillin. Antagonism with ciprofloxacin. Betamethasone : Increased hyperglycaemia and hypokalaemia with thiazide diuretics. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Potentially Fatal: Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Enhanced effect in women taking oestrogens or oral contraceptives.

Adverse Effects

Side effects of Fucidic Acid + Betamethasone Topical : Prolonged intensive treatment may cause local atrophic changes in the skin e.g. striae, thining and dilatation of superficial blood vessels. Dryness, itching, irritation, hypopigmentation, burning sensation at the site of application or miliaria.

Mechanism of Action

Betamethasone valerate is a topical corticosteroid that is effective in inflammatory dermatoses. Topical fusidic acid is effective against Staphyloccus aureus, Streptococci, Corynebacteria, Neisseria and some Clostridia and bacteroides. Antibacterial activity of fusidic acid is not reduced when used with betamethasone.

Note

Fusigen B Ointment manufactured by Geno Pharmaceuticals Ltd.. Its generic name is Fucidic Acid + Betamethasone Topical. Fusigen B is availble in Nepal. Farmaco Nepal drug index information on Fusigen B Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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