Fuzon Tablet

Alfuzosin
10mg
Time Pharmaceuticals Pvt. Ltd.
Pack size 100's
Dispensing mode
Source
Agent
Retail Price 18.00 NPR

Indications

Fuzon Tablet is used for: Benign prostatic hyperplasia (BPH)

Adult Dose

Oral Benign prostatic hyperplasia Adult: 2.5 mg tid. Max: 10 mg/day. 1st dose should be given before bedtime. Extended-release: 10 mg once daily. Elderly: Initially, 2.5 mg bid. Acute urinary retention: Extended-release: 10 mg once daily to be taken from 1st day of catheterisation. Duration: 3-4 days. Hepatic impairment: Mild to moderate: Initially, 2.5 mg daily, may increase to 2.5 mg bid according to response. Severe: Contraindicated.

Child Dose

Renal Dose

Renal Impairment Initially, 2.5 mg bid. Adjust dose according to response.

Administration

Administration Should be taken with food. Swallow whole. Extended-Release: Should be taken with food. Take immediately after the same meal each day. Swallow whole, do not chew/crush.

Contra Indications

Severe hepatic impairment; history of postural hypotension and micturition syncope; intestinal occlusion; severe renal insufficiency; lactation.

Precautions

Elderly; hypertension; coronary insufficiency; angina (discontinue); renal or hepatic impairment. Monitor BP regularly. May affect ability to drive or operate machinery.

Pregnancy-Lactation

Interactions

Additive effect on QT interval prolongation when used w/ QT-prolonging drugs. Concomitant admin w/ other ?1-adrenergic blocking agents, atenolol or diltiazem may result in additive CV effects. Increased plasma alfuzosin concentrations w/ cimetidine. Potentially Fatal: Concurrent use w/ potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) increase plasma alfuzosin levels.

Adverse Effects

Side effects of Alfuzosin : 1-10% Abdominal pain (1-2%),Back pain (1-2%),Brochitis (1-2%),Constipation (1-2%),Dizziness (5.7%),Dyspepsia (1-2%),Fatigue (2.7%),Headache (3%),Impotence (1-2%),Nausea (1-2%),Pharyngitis (1-2%),URT infection (3%),Sinusitis (1-2%),Upper respiratory infection (3%)

Mechanism of Action

Alfuzosin is a quinazoline derivative which exhibits selectivity for alpha1-adrenergic receptors in the lower urinary tract. Blockade of these adrenoreceptors causes relaxation of smooth muscle in the bladder neck and prostate, resulting in improvement in urine flow and a reduction in symptoms of benign prostatic hyperplasia (BPH).

Note

Fuzon 10mg Tablet manufactured by Time Pharmaceuticals Pvt. Ltd.. Its generic name is Alfuzosin. Fuzon is availble in Nepal. Farmaco Nepal drug index information on Fuzon Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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