Genticyn B Eye Drop
Betamethasone 0.05% + Gentamicin 0.1% E/E prep
Abbott India Ltd.
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Indications
Genticyn B Eye Drop is used for:
Ocular and ear inflammation with bacterial infection
Adult Dose
Adult: Ophth Ocular inflammation with suspected or confirmed bacterial infection As soln containing gentamicin 0.3% and betamethasone 0.1%: Instill 2 drops 3-4 times/day; acute stage: 2 drops 2 hrly. Per g oint contains gentamicin 3 mg and betamethasone 1 mg: Apply ¼ inch 3-4 times/day.
Otic Otic inflammation w/ suspected or confirmed bacterial infection As soln containing gentamicin 0.3% and betamethasone 0.1%: Instill 3-4 drops 3 times/day.
Child Dose
Safety and efficacy have not been established in children <8 yr.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Ophthalmic preparations should not be used in epithelial herpes simplex keratitis (dendritic keratitis), varicella, and many other viral diseases of the cornea and conjunctiva, mycobacterial infections of the eye, trachoma, fungal diseases of ocular structures. Not to be used after removal of a corneal foreign body or in the presence of acute local viral lesions e.g. herpes, and in patients with absent or perforated tympanic membranes.
Precautions
Prolonged ophthalmic usage may increase the intraocular pressure. Monitor intraocular pressure if treatment lasts for >10 days. Prolonged use of ophthalmic corticosteroid may increase the risk of cataract formation. Increases the risk of perforation in diseases causing thinning of the cornea or sclera. Use of topical corticosteroids may lead to reactivation of disease in patients with a history of herpetic infection of the cornea.
Steroid use after cataract surgery may increase risk of filtering blebs and delay healing. Prolonged use may also suppress immune response and increase risk of secondary infections. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Betamethasone 0.05% + Gentamicin 0.1% E/E prep :
Ophthalmic: Increased ocular pressure, increased ocular hyperemia, oedema and burning sensation. May also cause anterior uveitis or perforation of the globe. Otic: May cause ototoxicity.
Mechanism of Action
Betamethasone is a corticosteroid that has anti-inflammatory activity. Gentamicin is an aminoglycoside that has broad spectrum bactericidal activity; it is active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
Note
Genticyn B Eye Drop manufactured by Abbott India Ltd.. Its generic name is Betamethasone 0.05% + Gentamicin 0.1% E/E prep. Genticyn B is availble in Nepal.
Farmaco Nepal drug index information on Genticyn B Eye Drop is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.