Globac PM Tablet
Iron (Ferrous calcium citrate) + Folic acid
Cadila Pharmaceuticals Limited.
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| Retail Price | 7.69 NPR |
Indications
Globac PM Tablet is used for:
Iron deficiency anaemia
Adult Dose
Oral
Adult
1 caplet once a day
Child Dose
Renal Dose
Administration
For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation
Contra Indications
Patients with a known hypersensitivity to any of the ingredients. Hemochromatosis, hemosiderosis, hemolytic anemia.
Precautions
Iron chelates with antacid and tetracycline and absorption of all these may be impaired.
Pregnancy-Lactation
Interactions
Ferrous Sulphate: Oral absorption of iron may be increased when taken with ascorbic acid. May reduce the absorption of quinolones and tetracyclines when taken concurrently via the oral route. Concurrent admin with antacids may reduce the absorption of ferrous fumarate from the GI tract. May reduce the absorption of penicillamine in the gut when taken concurrently.
Folic Acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Adverse Effects
Side effects of Iron (Ferrous calcium citrate) + Folic acid :
GI disturbance including constipation, diarrhoea, dark stools. Dizziness, Headache, Nausea, Heartburn and epi-gastric pain.
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Note
Globac PM Tablet manufactured by Cadila Pharmaceuticals Limited.. Its generic name is Iron (Ferrous calcium citrate) + Folic acid. Globac PM is availble in Nepal.
Farmaco Nepal drug index information on Globac PM Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.