Gravidin Injection
Allystrenol
500mg
Zydus Pharmaceuticals
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Available as:
Indications
Gravidin Injection is used for:
Threatened miscarriage, Premature labor
Adult Dose
Adult: PO 5 mg 3 times/day for 5-7 days.
Child Dose
Renal Dose
Administration
Administration May be taken with or without food. May be taken w/ meals if GI upset occurs.
Contra Indications
Hypersensitivity; thrombophleobitis; undiagnosed vag bleeding, incomplete abortion, hormone-dependent carcinoma, cerebral apoplexy, as a diagnostic test for pregnancy; severe hepatic impairment; pregnancy.
Precautions
Discontinue medications if there is sudden partial or complete loss of vision, proptosis or diplopia; migraine and embolic disorders; epilepsy, migraine, asthma, cardiac or renal dysfunction. History of depression, glucose tolerance and diabetic patients. My impair ability to drive operate machinery. Sudden withdrawal of allyloestrenol should be avoided as it leads to intermittent breakthrough bleeding; lactation.
Pregnancy-Lactation
Interactions
Enhanced clearance with enzyme-inducing drugs eg, carbamazepine, griseofulvin, phenobarbital, phenytoin and rifampicin. Ketoconazole may increase bioavailability of progesterone.
Potentially Fatal: Increased ciclosporin concentration.
Adverse Effects
Side effects of Allystrenol :
GI disturbances, appetite/weight change; fluid retention, oedema; acnes, skin rash, urticaria; depression, headache, fever, fatigue; breast changes, hirsutism, changes in libido, altered menstrual cycles or irregular menstrual bleeding (rare).
Mechanism of Action
Allylestrenol is similar to that of natural progesterone. It prepares the uterus for receiving the fertilised ovum and suppresses uterine motility.
Note
Gravidin 500mg Injection manufactured by Zydus Pharmaceuticals. Its generic name is Allystrenol. Gravidin is availble in Nepal.
Farmaco Nepal drug index information on Gravidin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.