Hyalu Gel Gel

Hyaluronic Acid Sodium Salt (Sodium hyaluronate)
1%
Ethicare Remedies
Pack size
Dispensing mode
Source
Agent
Retail Price 424.00 NPR

Indications

Hyalu Gel Gel is used for: Osteoarthritis

Adult Dose

Intra-articular Osteoarthritis of the knee Adult: 20-25 mg once wkly for 5 wk or up to 30 mg once wkly for 3-4 wk. Not to repeat treatment course within 6 mth for any individual joint.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity to sodium hyaluronate or avian proteins.

Precautions

Do not concomitantly use disinfectants containing quaternary ammonium salts for skin preparation because hyaluronic acid can precipitate in their presence. Inject subcutaneous lidocaine or similar local anesthetic prior to injection of hyaluronate. Remove joint effusion, if present, before injection. Do not use the same syringe for removing joint effusion and for injecting hyaluronate.The vial/syringe is intended for single use. Lactation: Unknown whether distributed in breast milk, caution advised

Pregnancy-Lactation

Interactions

The safety and effectiveness of the use of sodium hyaluronate concomitantly with other intra-articular injection has not yet been established. As sodium hyaluronate is precipitated by quaternary amine bactericides or disinfectants eg, benzalkonium chloride and chlorhexidine, etc, adequate attention should be given.

Adverse Effects

Side effects of Hyaluronic Acid Sodium Salt (Sodium hyaluronate) : >10% Arthralgia (25%),Tenderness (61-92%),Swelling (81-91%),Firmness (88-89%),Bruising (52-87%),Pruritus (25-36%),Skin discoloration (33-78%),Firmness (86-89%),Lumps/bumps (56-83%) 1-10% Increased blood pressure (4%),Fatigue (1%),Nausea (<2%),Injection site pain (3%),Paresthesia (1%),Tendonitis (2%),Limb pain (1%),Tendonitis (2%),Joint effusion (2%) <1% Angioedema,Arthritis,Herpetic eruptions,Thrombocytopenia,Peripheral edema,Vasovagal reaction,Hives,Gait disturbances

Mechanism of Action

Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.

Note

Hyalu Gel 1% Gel manufactured by Ethicare Remedies. Its generic name is Hyaluronic Acid Sodium Salt (Sodium hyaluronate). Hyalu Gel is availble in Nepal. Farmaco Nepal drug index information on Hyalu Gel Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Hyaluronic Acid Sodium Salt (Sodium hyaluronate) :